Evidence map›Paper›PMID 28716147›Full record

Trial reportTrials2017

STOP smoking and alcohol drinking before OPeration for bladder cancer (the STOP-OP study), perioperative smoking and alcohol cessation intervention in relation to radical cystectomy: study protocol for a randomised controlled trial.

Susanne Vahr Lauridsen, Thordis Thomsen, Peter Thind, Hanne Tønnesen

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02188446 (Randomised Controlled Multicenter Study.Effect of an Intensive Smoking- and/or Alcohol Cessation Intervention Placed Shortly Before and 5 Weeks After Bladder Cancer Surgery on Postoperative Complications), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02188446 nacompletednot on this map

Randomised Controlled Multicenter Study.Effect of an Intensive Smoking- and/or Alcohol Cessation Intervention Placed Shortly Before and 5 Weeks After Bladder Cancer Surgery on Postoperative Complications

TypeinterventionalSponsorRigshospitalet, DenmarkRan2014 to 2018Enrolled105ConditionsBladder Cancer, Smoking, Alcohol ConsumptionArmsEducational programme for smoking and alcohol cessation
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Preoperative patient preparation in enhanced recovery pathways.Journal of anaesthesiology, clinical pharmacology · 2019
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Susanne Vahr LauridsenDepartment of Urology, Copenhagen University Hospital, Rigshospitalet, 2112, Blegdamsvej 9, 2100, Copenhagen, Denmark. Susanne.vahr@regionh.dk.
Thordis ThomsenAbdominal Centre, Copenhagen University Hospital, Rigshospitalet and University of Copenhagen, Health and Medical Sciences, Copenhagen, Denmark.
Peter ThindDepartment of Urology, Copenhagen University Hospital, Rigshospitalet, 2112, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Hanne TønnesenClinical Health Promotion Centre, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospitals, Copenhagen, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the effect of a smoking-, alcohol- or combined-cessation intervention starting shortly before surgery and lasting 6 weeks on overall complications after radical cystectomy. Secondary objectives are to examine the effect on types and grades of complications, smoking cessation and alcohol cessation, length of hospital stay, health-related quality of life and return to work or habitual level of activity up to 12 months postoperatively. METHODS/

designThe study is a multi-institutional randomised clinical trial involving 110 patients with a risky alcohol intake and daily smoking who are scheduled for radical cystectomy. Patients will be randomised to the 6-week Gold Standard Programme (GSP) or treatment as usual (control). The GSP combines patient education and pharmacologic strategies. Smoking and alcohol intake is biochemically validated (blood, urine and breath tests) at the weekly meetings and at follow-up. DISCUSSION: Herein, we report the design of the STOP-OP study, objectives and accrual up-date. This study will provide new knowledge about how to prevent smoking and alcohol-related postoperative complications at the time of bladder cancer surgery. Till now 77 patients have been enrolled. Patient accrual is expected to be finalised before the end of 2017 and data will be published in 2018.

trial registrationClinicalTrials.gov, ID: NCT02188446 . Registered on 28 May 2014.

Indexed as

Alcohol AbstinenceCystectomyAlcohol DrinkingClinical ProtocolsDenmarkHealth Knowledge, Attitudes, PracticeHumansPatient Education as TopicPostoperative ComplicationsResearch DesignRisk FactorsSmokingSmoking CessationTime FactorsTreatment OutcomeUrinary Bladder NeoplasmsAlcoholBladder cancerpostoperative complicationsSmokingSurgery

Identifiers

PMID28716147
PMCPMC5513198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.