ArticleBMC genomics2017
Ethylene induces combinatorial effects of histone H3 acetylation in gene expression in Arabidopsis.
Article in BMC genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 65 citations in OpenAlex.
- Studies on the mother flower carnation: past, present, and future.Horticulture research · 2025Article
- Histone acetyltransferase HAF2 associates with pyruvate dehydrogenase complex to control H3K14ac and H3K23ac in ethylene response.Cell reports · 2025Article
- High-throughput capture of transcription factor-driven epigenome dynamics using PHILO ChIP-seq.Nucleic acids research · 2024Article
- Constitutive expression of cucumber CsACS2 in Arabidopsis Thaliana disrupts anther dehiscence through ethylene signaling and DNA methylation pathways.Plant cell reports · 2024Article
- Cytokinins regulate spatially specific ethylene production to control root growth in Arabidopsis.Plant communications · 2024Article
- How chromatin senses plant hormones.Current opinion in plant biology · 2024Review
- Ethylene, a Signaling Compound Involved in Seed Germination and Dormancy.Plants (Basel, Switzerland) · 2024Review
- Chromatin sensing: integration of environmental signals to reprogram plant development through chromatin regulators.Journal of experimental botany · 2024Review
- HISTONE DEACETYLASE19 Controls Ovule Number Determination and Transmitting Tract Differentiation.Plant physiology · 2024Article
- DNA methylation remodeled amino acids biosynthesis regulates flower senescence in carnation (Dianthus caryophyllus).The New phytologist · 2024Article
- Normal distribution of H3K9me3 occupancy co-mediated by histone methyltransferase BcDIM5 and histone deacetylase BcHda1 maintains stable ABA synthesis inFrontiers in microbiology · 2024Article
- An insertion of transposon in DcNAP inverted its function in the ethylene pathway to delay petal senescence in carnation (Dianthus caryophyllus L.).Plant biotechnology journal · 2023Article
- Histone Deacetylase Inhibitor, Sodium Butyrate-Induced Metabolic Modulation inInternational journal of molecular sciences · 2023Article
- Histone H3K4 methyltransferase DcATX1 promotes ethylene induced petal senescence in carnation.Plant physiology · 2023Article
- Variations inGenes · 2023Article
- Phosphorylation status of Bβ subunit acts as a switch to regulate the function of phosphatase PP2A in ethylene-mediated root growth inhibition.The New phytologist · 2022Article
- Article
- Epigenetics and its role in effecting agronomical traits.Frontiers in plant science · 2022Review
- ENAP1 retrains seed germination via H3K9 acetylation mediated positive feedback regulation of ABI5.PLoS genetics · 2021Article
- Modulation of Organogenesis and Somatic Embryogenesis by Ethylene: An Overview.Plants (Basel, Switzerland) · 2021Review
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundHistone acetylation and deacetylation are essential for gene regulation and have been implicated in the regulation of plant hormone responses. Many studies have indicated the role of histone acetylation in ethylene signaling; however, few studies have investigated how ethylene signaling regulates the genomic landscape of chromatin states. Recently, we found that ethylene can specifically elevate histone H3K14 acetylation and the non-canonical histone H3K23 acetylation in etiolated seedlings and the gene activation is positively associated with the elevation of H3K14Ac and H3K23Ac in response to ethylene. To assess the role of H3K9, H3K14, and H3K23 histone modifications in the ethylene response, we examined how ethylene regulates histone acetylation and the transcriptome at global level and in ethylene regulated genes both in wild type (Col-0) and ein2-5 seedlings.
resultsOur results revealed that H3K9Ac, H3K14Ac, and H3K23Ac are preferentially enriched around the transcription start sites and are positively correlated with gene expression levels in Col-0 and ein2-5 seedlings both with and without ethylene treatment. In the absence of ethylene, no combinatorial effect of H3K9Ac, H3K14Ac, and H3K23Ac on gene expression was detected. In the presence of ethylene, however, combined enrichment of the three histone acetylation marks was associated with high gene expression levels, and this ethylene-induced change was EIN2 dependent. In addition, we found that ethylene-regulated genes are expressed at medium or high levels, and a group of ethylene regulated genes are marked by either one of H3K9Ac, H3K14Ac or H3K23Ac. In this group of genes, the levels of H3K9Ac were altered by ethylene, but in the absence of ethylene the levels of H3K9Ac and peak breadths are distinguished in up- and down- regulated genes. In the presence of ethylene, the changes in the peak breadths and levels of H3K14Ac and H3K23Ac are required for the alteration of gene expressions.
conclusionsOur study reveals that the plant hormone ethylene induces combinatorial effects of H3K9Ac, K14Ac and K23Ac histone acetylation in gene expression genome widely. Further, for a group of ethylene regulated genes, in the absence of ethylene the levels and the covered breadths of H3K9Ac are the preexist markers for distinguishing up- and down- regulated genes, the change in the peak breadths and levels of H3K14Ac and H3K23Ac are required for the alteration of gene expression in the presence of ethylene.
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