Evidence map›Paper›PMID 28716003›Full record

Trial reportBMC geriatrics2017

Eccentric versus traditional resistance exercise for older adult fallers in the community: a randomized trial within a multi-component fall reduction program.

Paul LaStayo, Robin Marcus, Leland Dibble, Bob Wong, Ginette Pepper

2 registry-linked trialsAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC geriatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01080196 nacompletednot on this map

Reducing Falls With RENEW in Older Adults Who Have Fallen

TypeinterventionalSponsorUniversity of UtahRan2008 to 2014Enrolled134ConditionsMuscle Atrophy, Physical DeconditioningArmsRENEW
NCT04099316 naunknown statusnot on this map

Effects of Eccentric-based Training on Muscle Strength and Physical Function in Older Adults

TypeinterventionalSponsorSeoul National University Bundang HospitalRan2017 to 2019Enrolled27ConditionsSarcopeniaArmsEccentric exercise, Conventional resistance exercise
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  3. Exercise for preventing falls in older people living in the community.The Cochrane database of systematic reviews · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paul LaStayoDepartment of Physical Therapy and Athletic Training, University of Utah, 520 Wakara Way, Salt Lake City, UT, 84109, USA. paul.lastayo@hsc.utah.edu.ORCID 0000-0001-6867-4077
Robin MarcusDepartment of Physical Therapy and Athletic Training, University of Utah, 520 Wakara Way, Salt Lake City, UT, 84109, USA.
Leland DibbleDepartment of Physical Therapy and Athletic Training, University of Utah, 520 Wakara Way, Salt Lake City, UT, 84109, USA.
Bob WongCollege of Nursing, University of Utah, Salt Lake City, UT, USA.
Ginette PepperCollege of Nursing, University of Utah, Salt Lake City, UT, USA.

Funding

Reducing Falls with RENEW in Older Individuals Who Have FallenR01AG031255 · NIA · UNIVERSITY OF UTAH · PI LASTAYO, PAUL C · 2008 to 2012
$2.2M
NIA NIH HHS R01 AG031255
6 · The paper itself

Abstract

backgroundAddressing muscle deficits within a multi-component exercise fall reduction program is a priority, especially for the highest risk older adults, i.e., those who have fallen previously. Eccentric resistance exercise with its high-force producing potential, at a low energetic cost, may be ideally-suited to address muscle impairments in this population. The purpose of this study was to compare the effects of resistance exercise via negative, eccentrically-induced, work (RENEW) versus traditional (TRAD) resistance exercise on mobility, balance confidence, muscle power and cross sectional area, as well as the number of days high fall risk older adults survived without a fall event over a 1 year period.

methodsRandomized, two group, four time point (over 1 year) clinical trial testing RENEW versus TRAD as part of a 3 month multi-component exercise fall reduction program (MCEFRP). Primary outcomes of mobility, balance confidence, muscle power output and cross sectional area were analyzed using mixed effects modeling. The secondary outcomes of days to fall and days to near-fall were analyzed using survival analysis.

resultsThe MCEFRP did have an effect on fall risk factors considered reversible with exercise interventions though there was no differential effect of RENEW versus TRAD (p = 0.896) on mobility, balance confidence, muscle power and cross sectional area. There were also no group differences in the number of days survived without a fall (p = 0.565) or near-fall (p = 0.678). Despite 100% of participants having at least one fall in the year prior to the MCEFRP, however, after 3 months of exercise and 9 months of follow-up <50% had experienced a fall or near fall.

conclusionsThere were no differential effects of RENEW or TRAD as components of a MCEFRP on the primary or secondary outcomes. The two modes of resistance exercise had identical effects on fall risk and fall-free survival.

trial registrationNCT01080196 ; March 2, 2010 (retrospectively registered).

Indexed as

Independent LivingAccidental FallsAgedAged, 80 and overExerciseExercise TestExercise TherapyFemaleHumansMalePostural BalanceResistance TrainingRisk FactorsAgingEccentricExerciseFallsPrevention

Identifiers

PMID28716003
PMCPMC5513167

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.