Evidence map›Paper›PMID 28715478›Full record

ArticlePloS one2017

Loneliness is adversely associated with physical and mental health and lifestyle factors: Results from a Swiss national survey.

Aline Richard, Sabine Rohrmann, Caroline L Vandeleur, Margareta Schmid, Jürgen Barth, Monika Eichholzer

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
138citing papers in PubMed, 3 pooled it
26.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

138 citing papers in PubMed, 3 syntheses or guidelines pooled it, 343 citations in OpenAlex.

  1. Pooled it
  2. Loneliness and the onset of new mental health problems in the general population.Social psychiatry and psychiatric epidemiology · 2022
    Pooled it
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  6. The Silent Chief Complaint.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2026
    Article
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  10. The association between loneliness and quality of life in cancer survivors: All of Us research program.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  19. Review
  20. Loneliness in Resettlement Among Multi-Ethnic Resettled Refugees in Ohio.Journal of racial and ethnic health disparities · 2025
    Article

78 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aline RichardEpidemiology, Biostatistics and Prevention Institute, Division of Chronic Disease Epidemiology, University of Zurich, Hirschengraben 84, Zurich, Switzerland.ORCID http://orcid.org/0000-0003-3292-0197
Sabine RohrmannEpidemiology, Biostatistics and Prevention Institute, Division of Chronic Disease Epidemiology, University of Zurich, Hirschengraben 84, Zurich, Switzerland.
Caroline L VandeleurCentre for Research in Psychiatric Epidemiology and Psychopathology, Department of Psychiatry, University Hospital of Lausanne, Site de Cery, Prilly, Switzerland.
Margareta SchmidEpidemiology, Biostatistics and Prevention Institute, Division of Chronic Disease Epidemiology, University of Zurich, Hirschengraben 84, Zurich, Switzerland.
Jürgen BarthInstitute for Complementary and Integrative Medicine, University Hospital and University of Zurich, Sonneggstr. 6, Zurich, Switzerland.
Monika EichholzerEpidemiology, Biostatistics and Prevention Institute, Division of Chronic Disease Epidemiology, University of Zurich, Hirschengraben 84, Zurich, Switzerland.
University of Zurich · CHUniversity Hospital of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLoneliness is a common, emotionally distressing experience and is associated with adverse physical and mental health and an unhealthy lifestyle. Nevertheless, little is known about the prevalence of loneliness in different age groups in Switzerland. Furthermore, the existing evidence about age and gender as potential effect modifiers of the associations between loneliness, physical and mental health and lifestyle characteristics warrants further investigation. Thus, the aim of the study was to examine the prevalence of loneliness among adults in Switzerland and to assess the associations of loneliness with several physical and mental health and behavioral factors, as well as to assess the modifying effect of sex and age.

methodsData from 20,007 participants of the cross-sectional population-based Swiss Health Survey 2012 (SHS) were analyzed. Logistic regression analyses were used to assess associations of loneliness with physical and mental health or lifestyle characteristics (e.g. diabetes, depression, physical activity). Wald tests were used to test for interactions.

resultsLoneliness was distributed in a slight U-shaped form from 15 to 75+ year olds, with 64.1% of participants who had never felt lonely. Lonely individuals were more often affected by physical and mental health problems, such as self-reported chronic diseases (Odds ratio [OR] 1.41, 95% confidence interval [CI] 1.30-1.54), high cholesterol levels (OR 1.31, 95% CI 1.18-1.45), diabetes (OR 1.40, 95% CI 1.16-1.67), moderate and high psychological distress (OR 3.74, 95% CI 3.37-4.16), depression (OR 2.78, 95% CI 2.22-3.48) and impaired self-perceived health (OR 1.94, 95% CI 1.74-2.16). Loneliness was significantly associated with most lifestyle factors (e.g. smoking; OR 1.13, 95% 1.05-1.23). Age, but not sex, moderated loneliness' association with several variables.

conclusionLoneliness is associated with poorer physical and mental health and unhealthy lifestyle, modified by age, but not by sex. Our findings illustrate the importance of considering loneliness for physical and mental health and lifestyle factors, not only in older and younger, but also in middle-aged adults. Longitudinal studies are needed in Switzerland to elucidate the causal relationships of these associations.

Indexed as

Life StyleMental HealthAdolescentAdultAgedAge FactorsCross-Sectional StudiesDepressionDiabetes ComplicationsExerciseFemaleHealth SurveysHumansLonelinessMaleMiddle Aged

Identifiers

PMID28715478
PMCPMC5513556
OpenAlexW2735785644

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.