Evidence map›Paper›PMID 28715374›Full record

ArticleJournal of visualized experiments : JoVE2017

In Vivo Evaluation of the Mechanical and Viscoelastic Properties of the Rat Tongue.

Emanuele Loro, Stephen H Wang, Richard J Schwab, Tejvir S Khurana

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Emanuele LoroDepartment of Physiology and Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania.
Stephen H WangCenter for Sleep & Circadian Neurobiology, University of Pennsylvania.
Richard J SchwabCenter for Sleep & Circadian Neurobiology, University of Pennsylvania; rschwab@mail.med.upenn.edu.
Tejvir S KhuranaDepartment of Physiology and Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania; tsk@mail.med.upenn.edu.
University of Pennsylvania · US

Funding

Understanding the relationship between obesity and tongue fat in humans and ratsP01HL094307 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI PACK, ALLAN I · 2009 to 2020
$23.7M
Obesity & OSA: Understanding the Importance of Tongue Fat and Metabolic FunctionR01HL089447 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI SCHWAB, RICHARD J. · 2008 to 2011
$2.4M
NHLBI NIH HHS P01 HL094307NHLBI NIH HHS R01 HL089447
6 · The paper itself

Abstract

The tongue is a highly innervated and vascularized muscle hydrostat on the floor of the mouth of most vertebrates. Its primary functions include supporting mastication and deglutition, as well as taste-sensing and phonetics. Accordingly, the strength and volume of the tongue can impact the ability of vertebrates to accomplish basic activities such as feeding, communicating, and breathing. Human patients with sleep apnea have enlarged tongues, characterized by reduced muscle tone and increased intramuscular fat that can be visualized and quantified by magnetic resonance imaging (MRI). The abilities to measure force generation and viscoelastic properties of the tongue constitute important tools for obtaining functional information to correlate with imaging data. Here, we present techniques for measuring tongue force production in anesthetized Zucker rats via electrical stimulation of the hypoglossal nerves and for determining the viscoelastic properties of the tongue by applying passive Lissajous force/deformation curves.

Indexed as

AnimalsHypoglossal NerveModels, AnimalRatsTongue

Identifiers

PMID28715374
PMCPMC5609307
OpenAlexW2727743478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.