Evidence map›Paper›PMID 28715160›Full record

ArticleJournal of the International AIDS Society2017

Meeting the WHO 90% target: antiretroviral treatment efficacy in Poland is associated with baseline clinical patient characteristics.

Milosz Parczewski, Ewa Siwak, Magdalena Leszczyszyn-Pynka, Iwona Cielniak, Ewa Burkacka, Piotr Pulik, Adam Witor, Karolina Muller, Ewelina Zasik, Anna Grzeszczuk and 22 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Observational
  3. Impact of HIV co-infection on liver fibrosis regression after HCV treatment.Revista do Instituto de Medicina Tropical de Sao Paulo · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors at 11 institutions in 1 country.

Milosz ParczewskiPomeranian Medical University, Department of Infectious, Tropical Diseases and Immune Deficiency, Szczecin, Poland.
Ewa SiwakHospital for Infectious Diseases, HIV Out-Patient's Clinic, Warsaw, Poland.
Magdalena Leszczyszyn-PynkaPomeranian Medical University, Department of Infectious, Tropical Diseases and Immune Deficiency, Szczecin, Poland.
Iwona CielniakHospital for Infectious Diseases, HIV Out-Patient's Clinic, Warsaw, Poland.
Ewa BurkackaHospital for Infectious Diseases, HIV Out-Patient's Clinic, Warsaw, Poland.
Piotr PulikHospital for Infectious Diseases, HIV Out-Patient's Clinic, Warsaw, Poland.
Adam WitorRegional Hospital, Out-Patient's Clinic for Immune Deficiency, Chorzów, Poland.
Karolina MullerRegional Hospital, Out-Patient's Clinic for Immune Deficiency, Chorzów, Poland.
Ewelina ZasikRegional Hospital, Out-Patient's Clinic for Immune Deficiency, Chorzów, Poland.
Anna GrzeszczukDepartment of Infectious Diseases and Hepatology, Medical University of Białystok, Białystok, Poland.
Maria JankowskaDepartment of Infectious Diseases, Medical University of Gdańsk, Gdańsk, Poland.
Małgorzata LemańskaDepartment of Infectious Diseases, Medical University of Gdańsk, Gdańsk, Poland.
Anita OlczakDepartment of Infectious Diseases and Hepatology Nicolaus Copernicus University Ludwik Rydygier Collegium Medicum in Bydgoszcz, Faculty of Medicine, Bydgoszcz, Poland.
Edyta GrąbczewskaDepartment of Infectious Diseases and Hepatology Nicolaus Copernicus University Ludwik Rydygier Collegium Medicum in Bydgoszcz, Faculty of Medicine, Bydgoszcz, Poland.
Aleksandra SzymczakDepartment of Infectious Diseases, Liver Disease and Acquired Immune Deficiencies, Wroclaw Medical University, Wrocław, Poland.
Jacek GąsiorowskiDepartment of Infectious Diseases, Liver Disease and Acquired Immune Deficiencies, Wroclaw Medical University, Wrocław, Poland.
Bartosz SzetelaDepartment of Infectious Diseases, Liver Disease and Acquired Immune Deficiencies, Wroclaw Medical University, Wrocław, Poland.
Monika Bociąga-JasikDepartment of Infectious Diseases, Jagiellonian University Medical College, Kraków, Poland.
Paweł SkwaraDepartment of Infectious Diseases, Jagiellonian University Medical College, Kraków, Poland.
Magdalena Witak-JędraPomeranian Medical University, Department of Infectious, Tropical Diseases and Immune Deficiency, Szczecin, Poland.
Elżbieta JabłonowskaDepartment of Infectious Diseases and Hepatology, Medical University of Łódź, Łódź, Poland.
Kamila Wójcik-CichyDepartment of Infectious Diseases and Hepatology, Medical University of Łódź, Łódź, Poland.
Juliusz KamerysDepartment of Infectious Diseases and Hepatology, Medical University of Łódź, Łódź, Poland.
Małgorzata JanczarekDepartment of Infectious Diseases and Hepatology, Medical University of Białystok, Białystok, Poland.
Dagny KrankowskaDepartment of Infectious and Tropical Diseases and Hepatology, Medical University in Warsaw, Warsaw, Poland.
Tomasz MikułaDepartment of Infectious and Tropical Diseases and Hepatology, Medical University in Warsaw, Warsaw, Poland.
Katarzyna KoziełDepartment of Infectious Diseases, Regional Hospital in Zielona Góra, Zielona Góra, Poland.
Dariusz BielecDepartment of Infectious Diseases, Medical University in Lublin, Lublin, Poland.
Justyna StempkowskaDepartment of Infectious Diseases, Medical University in Lublin, Lublin, Poland.
Aleksandra KocbachClinical Division of Infectious Diseases, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Wiesława BłudzinDepartment of Infectious Diseases, Regional Hospital, Opole, Poland.
Andrzej HorbanHospital for Infectious Diseases, HIV Out-Patient's Clinic, Warsaw, Poland.
Medical University of Warsaw · PLMedical University of Lodz · PLPomeranian Medical University · PLWroclaw Medical University · PLCollegium Medicum in Bydgoszcz · PLGdańsk Medical University · PLJagiellonian University · PLMedical University of Białystok · PLMedical University of Lublin · PLUniversity of Warmia and Mazury in Olsztyn · PLUniversity of Zielona Góra · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionModern combined antiretroviral therapies (cART) allow to effectively suppress HIV-1 viral load, with the 90% virologic success rate, meeting the WHO target in most clinical settings. The aim of this study was to analyse antiretroviral treatment efficacy in Poland and to identify variables associated with virologic suppression. M:

resultsVirologic suppression rates of <50 copies/mL were observed in 4672 (90.68%) and <200 copies/mL in 4934 (95.77%) individuals. In univariate analyses, for the suppression threshold <50 copies/mL higher efficacy was noted for 2NRTI+NNRTI-based combinations (94.73%) compared to 2NRTI+PI (89.93%), 2NRTI+InI (90.61%), nucleos(t)ide sparing PI/r+InI (82.02%) and three drug class regimens (74.49%) (

conclusionsProportion of virologically suppressed patients is in line with WHO treatment target confirming successful application of antiretroviral treatment strategy in Poland. Virological suppression rates depend on baseline patient characteristics, which should guide individualized antiretroviral tre0atment decisions.

Indexed as

AdultAge FactorsAnti-HIV AgentsCD4 Lymphocyte CountCross-Sectional StudiesDrug Therapy, CombinationFemaleHealth PlanningHIV-1HIV InfectionsHumansMaleMiddle AgedPolandTreatment OutcomeViral LoadAnti-HIV Agentsantiretroviral treatmentcART efficacyviral replicationvirologic controlvirologic suppressionWHO target

Identifiers

PMID28715160
PMCPMC5577695
OpenAlexW2734932982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.