ArticleGenes2017
Genetic Contribution to Alcohol Dependence: Investigation of a Heterogeneous German Sample of Individuals with Alcohol Dependence, Chronic Alcoholic Pancreatitis, and Alcohol-Related Cirrhosis.
Open access · goldAbstract read
In one paragraph
Article in Genes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 12 citations in OpenAlex.
- Article
- The complement system in liver diseases: Evidence-based approach and therapeutic options.Journal of translational autoimmunity · 2019Review
- Article
- Genetic determinants of beverage consumption: Implications for nutrition and health.Advances in food and nutrition research · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
42 authors at 18 institutions in 2 countries.
Jens TreutleinDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. jens.treutlein@zi-mannheim.de.
Josef FrankDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. josef.frank@zi-mannheim.de.
Fabian StreitDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. fabian.streit@zi-mannheim.de.
Céline S ReinboldHuman Genomics Research Group, Department of Biomedicine, University and University Hospital Basel, 4031 Basel, Switzerland. celine.reinbold@unibas.ch.
Dilafruz JuraevaDivision of Applied Bioinformatics (G200), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. juraeva@yahoo.com.
Franziska DegenhardtInstitute of Human Genetics, University of Bonn, 53127 Bonn, Germany. franziska.degenhardt@uni-bonn.de.
Liz RietschelUniversity Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, 3000 Bern 60, Switzerland. liz.rietschel@kjp.unibe.ch.
Stephanie H WittDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. stephanie.witt@zi-mannheim.de.
Andreas J ForstnerHuman Genomics Research Group, Department of Biomedicine, University and University Hospital Basel, 4031 Basel, Switzerland. forstner@uni-bonn.de.
Monika RidingerDepartment of Psychiatry and Psychotherapy, University of Regensburg, 93053 Regensburg, Germany. monika.ridinger@gmx.ch.
Jana StrohmaierDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. jana.strohmaier@zi-mannheim.de.
Norbert WodarzDepartment of Psychiatry and Psychotherapy, University of Regensburg, 93053 Regensburg, Germany. norbert.wodarz@medbo.de.
Helene DukalDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. helene.dukal@zi-mannheim.de.
Jerome C FooDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. jerome.foo@zi-mannheim.de.
Per HoffmannHuman Genomics Research Group, Department of Biomedicine, University and University Hospital Basel, 4031 Basel, Switzerland. per.hoffmann@unibas.ch.
Stefan HermsHuman Genomics Research Group, Department of Biomedicine, University and University Hospital Basel, 4031 Basel, Switzerland. stefan.herms@unibas.ch.
Stefanie Heilmann-HeimbachInstitute of Human Genetics, University of Bonn, 53127 Bonn, Germany. sheilman@uni-bonn.de.
Michael SoykaPrivate Hospital Meiringen, 3860 Meiringen, Switzerland. Michael.Soyka@privatklinik-meiringen.ch.
Wolfgang MaierDepartment of Psychiatry, University of Bonn, 53105 Bonn, Germany. Wolfgang.Maier@ukb.uni-bonn.de.
Wolfgang GaebelDepartment of Psychiatry and Psychotherapy, University of Düsseldorf, 40629 Düsseldorf, Germany. wolfgang.gaebel@uni-duesseldorf.de.
Norbert DahmenDepartment of Psychiatry, University of Mainz, 55131 Mainz, Germany. n.dahmen@oehk.de.
Norbert ScherbaumLVR-Hospital Essen, Department of Psychiatry and Psychotherapy, Medical Faculty, University of Duisburg-Essen, 45147 Essen, Germany. norbert.scherbaum@uni-due.de.
Bertram Müller-MyhsokDepartment of Statistical Genetics, Max-Planck-Institute of Psychiatry, 80804 Munich, Germany. bmm@mpipsykl.mpg.de.
Susanne LucaeDepartment of Psychiatric Pharmacogenetics, Max-Planck-Institute of Psychiatry, 80804 Munich, Germany. lucae@psych.mpg.de.
Marcus IsingDepartment of Molecular Psychology, Max-Planck-Institute of Psychiatry, 80804 Munich, Germany. ising@psych.mpg.de.
Felix StickelDepartment of Gastroenterology and Hepatology, University Hospital of Zurich, 8091 Zurich, Switzerland. Felix.stickel@uzh.ch.
Thomas BergSection of Hepatology, University Hospital Leipzig, 04103 Leipzig, Germany. Thomas.Berg@medizin.uni-leipzig.de.
Ulla RoggenbuckInstitute for Medical Informatics, Biometry, and Epidemiology, University Hospital of Essen, 45122 Essen, Germany. Ulla.Roggenbuck@uk-essen.de.
Karl-Heinz JöckelInstitute for Medical Informatics, Biometry, and Epidemiology, University Hospital of Essen, 45122 Essen, Germany. k-h.joeckel@uk-essen.de.
Henrike ScholzDepartment of Animal Physiology, University of Cologne, 50674 Cologne, Germany. henrike.scholz@uni-koeln.de.
Ulrich S ZimmermannDepartment of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Dresden Technical University, 01307 Dresden, Germany. UlrichS.Zimmermann@uniklinikum-dresden.de.
Stephan BuchMedical Department 1, University Hospital Dresden, TU Dresden, 01307 Dresden, Germany. Stephan.Buch@uniklinikum-dresden.de.
Wolfgang H SommerInstitute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. wolfgang.sommer@zi-mannheim.de.
Rainer SpanagelInstitute of Psychopharmacology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. rainer.spanagel@zi-mannheim.de.
Benedikt BrorsDivision of Applied Bioinformatics (G200), German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. b.brors@dkfz.de.
Sven CichonHuman Genomics Research Group, Department of Biomedicine, University and University Hospital Basel, 4031 Basel, Switzerland. sven.cichon@unibas.ch.
Karl MannDepartment of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. karl.mann@zi-mannheim.de.
Falk KieferDepartment of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. falk.kiefer@zi-mannheim.de.
Jochen HampeMedical Department 1, University Hospital Dresden, TU Dresden, 01307 Dresden, Germany. Jochen.Hampe@uniklinikum-dresden.de.
Jonas RosendahlDepartment of Internal Medicine I, Martin Luther University Halle, 06120 Halle (Saale), Germany. Jonas.Rosendahl@medizin.uni-leipzig.de.
Markus M NöthenInstitute of Human Genetics, University of Bonn, 53127 Bonn, Germany. markus.noethen@uni-bonn.de.
Marcella RietschelDepartment of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany. marcella.rietschel@zi-mannheim.de.
Heidelberg University · DEUniversity of Bonn · DEMax Planck Institute of Psychiatry · DEGerman Cancer Research Center · DEInstitut für Medizinische Informatik, Biometrie und Epidemiologie · DETechnische Universität Dresden · DEUniversity Hospital of Basel · CHUniversity of Regensburg · DEHeinrich Heine University Düsseldorf · DEJohannes Gutenberg University Mainz · DEMartin Luther University Halle-Wittenberg · DEPrivatklinik Meiringen · CHUniversity Hospital Carl Gustav Carus · DEUniversity Hospital Leipzig · DEUniversity Hospital of Zurich · CHUniversity of Bern · CHUniversity of Cologne · DEUniversity of Duisburg-Essen · DE
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study investigated the genetic contribution to alcohol dependence (AD) using genome-wide association data from three German samples. These comprised patients with: (i) AD; (ii) chronic alcoholic pancreatitis (ACP); and (iii) alcohol-related liver cirrhosis (ALC). Single marker, gene-based, and pathway analyses were conducted. A significant association was detected for the
Indexed as
ADH1BADH1Calcohol dehydrogenasealcohol dependencealcoholic liver cirrhosischronic alcoholic pancreatitisgenome-wide association study
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.