Evidence map›Paper›PMID 28714904›Full record

ArticleInternational journal of molecular sciences2017

BRD9 Inhibition, Alone or in Combination with Cytostatic Compounds as a Therapeutic Approach in Rhabdoid Tumors.

Katja F Krämer, Natalia Moreno, Michael C Frühwald, Kornelius Kerl

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Targeting Bromodomain-Containing Protein 9 in Human Uterine Fibroid Cells.Reproductive sciences (Thousand Oaks, Calif.) · 2025
    Article
  6. Chromatin remodellers as therapeutic targets.Nature reviews. Drug discovery · 2024
    Review
  7. Review
  8. Squamous Cell Carcinoma in Never Smokers: An Insight into SMARCB1 Loss.International journal of molecular sciences · 2024
    Article
  9. Identification and Development of BRD9 Chemical Probes.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  10. Article
  11. Article
  12. Review
  13. BRD9 Degradation Disrupts Ribosome Biogenesis in Multiple Myeloma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Katja F KrämerUniversity Children's Hospital Muenster, Department of Pediatric Hematology and Oncology, 48149 Münster, Germany. k_krae03@uni-muenster.de.
Natalia MorenoUniversity Children's Hospital Muenster, Department of Pediatric Hematology and Oncology, 48149 Münster, Germany. Natalia.MorenoGalarza@ukmuenster.de.
Michael C FrühwaldChildren's Hospital and Swabian Children's Cancer Center, 86156 Augsburg, Germany. michael.fruehwald@klinikum-augsburg.de.
Kornelius KerlUniversity Children's Hospital Muenster, Department of Pediatric Hematology and Oncology, 48149 Münster, Germany. Kornelius.Kerl@ukmuenster.de.
University Hospital Münster · DEUniversity Hospital Augsburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rhabdoid tumors (RT) are malignant neoplasms of early childhood. Despite intensive therapy, survival is poor and new treatment approaches are required. The only recurrent mutations in these tumors affect

Indexed as

BenzylaminesCarboplatinCell CycleCell Cycle CheckpointsCell Line, TumorCell ProliferationCell SurvivalCytostatic AgentsDoxorubicinDrug SynergismHumansInhibitory Concentration 50NaphthyridinesRhabdoid TumorSmall Molecule LibrariesVincristineBenzylaminesBI-9564CarboplatinCytostatic AgentsDoxorubicinNaphthyridinesSmall Molecule LibrariesVincristineBRD9rhabdoid tumorSWI/SNF complextargeted therapy

Identifiers

PMID28714904
PMCPMC5536025
OpenAlexW2734897764

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.