ReviewJournal of child psychology and psychiatry, and allied disciplines2018
Research Review: What have we learned about adolescent substance use?
Review in Journal of child psychology and psychiatry, and allied disciplines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 175 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
175 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Interventions for prevention and treatment of substance use in youth with traumatic childhood experiences: a systematic review and synthesis of the literature.European child & adolescent psychiatry · 2024Pooled it
- Neuroscience-informed classification of prevention interventions in substance use disorders: An RDoC-based approach.Neuroscience and biobehavioral reviews · 2024Pooled it
- The brain in social context: A systematic review of substance use and social processing from adolescence to young adulthood.Developmental cognitive neuroscience · 2022Pooled it
- Agreement between Youth Self-Report and Biospecimen-Confirmed Substance Use: A Systematic Review.Substance use & misuse · 2022Pooled it
- Pooled it
- Social isolation at adolescence: a systematic review on behaviour related to cocaine, amphetamine and nicotine use in rats and mice.Psychopharmacology · 2021Pooled it
- Efficacy of the Mexican version of the keepin' it REAL school-based prevention program in addressing multi-substance use from early to mid-adolescence.Drug and alcohol dependence · 2025Trial
- The effect of gamification-based training on the knowledge, attitudes, and academic achievement of male adolescents in preventing substance and internet addiction.BMC medical education · 2023Trial
- Co-Use of Some Substances Associated With Higher Doses in Adolescents: Findings From the Adolescent Brain Cognitive Development Study.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2026Article
- Leveraging Machine Learning to Understand the Link Between School Climate and Youth Substance Use: a Focus on Cannabis and Alcohol Use.Prevention science : the official journal of the Society for Prevention Research · 2026Article
- Talk to Me, Not Just My Parent: Teen and Caregiver Perspectives on Implementing Screening, Brief Intervention, and Referral to Treatment Equitably in Pediatric Inpatient Settings for Teens with Chronic Illness.Children (Basel, Switzerland) · 2026Article
- Substance Use Patterns in Pediatric Solid Organ Transplant Candidates: Impact After Transplant.Pediatric transplantation · 2026Article
- The Dysregulation Profile and Substance Use: Investigating Their Co-Variation From Adolescence to Emerging Adulthood.Emerging adulthood (Print) · 2026Article
- The Adolescent Brain Cognitive Development (ABCD) Study: Ten years of statistical and methodological contributions.Developmental cognitive neuroscience · 2026Article
- Parents Use Online Communities to Seek Guidance on Child Substance Use, Parental Use, and Family Substance Use Challenges: A Content Analysis of Reddit Posts.Journal of studies on alcohol and drugs · 2026Article
- Neighborhood Deprivation and Adolescent Mental Health: The Protective Role of School Staffing Patterns.Journal of the American Academy of Child and Adolescent Psychiatry · 2026Article
- Substance Use Patterns Across the Sexual Identity Spectrum Among U.S. Individuals.The American journal of psychiatry · 2026Article
- The HOPE program: protocol for a stratified cluster randomized controlled trial to prevent psychoactive substance use and promote health in Moroccan middle school students.Addiction science & clinical practice · 2026Article
- Beyond the offense: clinical correlates of repeated incarceration among justice-involved male adolescents with substance use disorder.Child and adolescent psychiatry and mental health · 2026Article
- Feasibility, Acceptability, and Utility of the Keepin' It REAL Program for Preventing Adolescent Substance Use in Nigeria.Journal of prevention (2022) · 2026Article
115 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
backgroundAdolescence is a critical biological, psychological, and social developmental stage involving heightened risk for substance use and associated adverse consequences. This review, synthesizing emerging findings on this complex topic, is intended to inform research and clinical care focused on adolescents.
methodsLiterature searches were conducted using PubMed, yielding a cross-section of observational and interventional studies focused on adolescent substance use. Findings were organized and categorized to cover key areas of epidemiology, neurobiology, prevention, and treatment.
findingsAdolescent substance-related attitudes and use patterns have evolved over time, informed by adult and peer behaviors, public policy, media messaging, substance availability, and other variables. A number of risk and resiliency factors contribute to individual differences in substance use and related consequences. Advances in observational techniques have provided enhanced understanding of adolescent brain development and its implications for substance use. Prevention efforts have yielded mixed results, and while a number of adolescent-targeted evidence-based treatments for substance use disorders have been developed, effect sizes are generally modest, indicating the need for further research to enhance prevention and treatment outcomes.
conclusionsSubstance use in adolescence is heterogeneous, ranging from normative to pathological, and can lead to significant acute and long-term morbidity and mortality. Understanding risk and resiliency factors, underlying neurobiology, and optimal developmentally sensitive interventions is critical in addressing substance-associated problems in adolescence.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.