Evidence map›Paper›PMID 28714174›Full record

ArticleMicrobial biotechnology2017

Immunological properties and protective efficacy of a single mycobacterial antigen displayed on polyhydroxybutyrate beads.

Patricia Rubio-Reyes, Natalie A Parlane, Bryce M Buddle, D Neil Wedlock, Bernd H A Rehm

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. AVaccines · 2021
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patricia Rubio-ReyesInstitute of Fundamental Sciences, Massey University, 11222 Private Bag, Palmerston North, New Zealand.
Natalie A ParlaneAgResearch, Hopkirk Research Institute, Grasslands Research Centre, 11008 Private Bag, Palmerston North, New Zealand.
Bryce M BuddleAgResearch, Hopkirk Research Institute, Grasslands Research Centre, 11008 Private Bag, Palmerston North, New Zealand.
D Neil WedlockAgResearch, Hopkirk Research Institute, Grasslands Research Centre, 11008 Private Bag, Palmerston North, New Zealand.
Bernd H A RehmInstitute of Fundamental Sciences, Massey University, 11222 Private Bag, Palmerston North, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2015, there were an estimated 10.4 million new tuberculosis (TB) cases and 1.4 million deaths worldwide. Bacille Calmette-Guérin (BCG), an attenuated strain of Mycobacterium bovis, is the vaccine available against TB, but it is insufficient for global TB control. This study evaluated the immunogenicity of the Mycobacterium tuberculosis antigen Rv1626 in mice while assessing the effect of co-delivering either Cpe30 (immunostimulatory peptide), CS.T3

Indexed as

AnimalsAntigens, BacterialBacterial ProteinsEscherichia coliFemaleGene ExpressionHumansHydroxybutyratesMiceMice, Inbred C57BLMycobacterium tuberculosisTh17 CellsTh1 CellsTuberculosisTuberculosis VaccinesAntigens, BacterialBacterial ProteinsHydroxybutyratesTuberculosis Vaccines

Identifiers

PMID28714174
PMCPMC5658617

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.