A reduction in SK channels contributes to increased activity of hypothalamic magnocellular neurons during heart failure.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

1. The brain-heart axis: effects of cardiovascular disease on the CNS and opportunities for central neuromodulation.Nature reviews. Neuroscience · 2026
   Review
2. Extended secondhand smoke exposure alters potassium channel activity and reduces excitability of cardiac vagal neurons in mice.Frontiers in physiology · 2026
   Article
3. Endoplasmic Reticulum and Mitochondrial Calcium Handling Dynamically Shape Slow Afterhyperpolarizations in Vasopressin Magnocellular Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
   Article
4. Impaired oxytocin signaling in the central amygdala in rats with chronic heart failure.bioRxiv : the preprint server for biology · 2023
   Article
5. Angiotensin II-Mediated Neuroinflammation in the Hippocampus Contributes to Neuronal Deficits and Cognitive Impairment in Heart Failure Rats.Hypertension (Dallas, Tex. : 1979) · 2023
   Article
6. Angiotensin II inhibits the A-type KAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2022
   Article
7. Heart failure impairs mood and memory in male rats and down-regulates the expression of numerous genes important for synaptic plasticity in related brain regions.Behavioural brain research · 2021
   Article
8. Cardiovascular Neuroendocrinology: Emerging Role for Neurohypophyseal Hormones in Pathophysiology.Endocrinology · 2021
   Review
9. Functional coupling between NMDA receptors and SK channels in rat hypothalamic magnocellular neurons: altered mechanisms during heart failure.The Journal of physiology · 2021
   Article
10. Three-dimensional morphometric analysis reveals time-dependent structural changes in microglia and astrocytes in the central amygdala and hypothalamic paraventricular nucleus of heart failure rats.Journal of neuroinflammation · 2020
    Article
11. Vasopressin & Oxytocin in Control of the Cardiovascular System: An Updated Review.Current neuropharmacology · 2020
    Review
12. Exacerbated effects of prorenin on hypothalamic magnocellular neuronal activity and vasopressin plasma levels during salt-sensitive hypertension.American journal of physiology. Heart and circulatory physiology · 2019
    Article
13. Transient receptor potential vanilloid type 4 is expressed in vasopressinergic neurons within the magnocellular subdivision of the rat paraventricular nucleus of the hypothalamus.The Journal of comparative neurology · 2018
    Article
14. Hypothalamic Ion Channels in Hypertension.Current hypertension reports · 2018
    Review
15. Hypothalamic neurons out of control.The Journal of physiology · 2017
    Article

Corrections and comments

• Commented on by
  Hypothalamic neurons out of control.2017

Authors and funding

3 authors at 2 institutions in 1 country.

Funding

Abstract

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