Evidence map›Paper›PMID 28713708›Full record

ArticleWorld journal of plastic surgery2017

The Healing Effect of Grape Seed Oil Enema with or without Sesame Oil in Acetic Acid Induced Ulcerative Colitis of Rats.

Fatemeh Hosseinzadeh, Moosa Salehi, Nader Tanideh, Davood Mehrabani, Azadeh Sayarifard, Anahita Sedighi

Open access · greenAbstract read
In one paragraph

Article in World journal of plastic surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Anti-Inflammatory, Antioxidant, and Healing-Promoting Effects ofEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  5. Article
  6. Article
  7. Grape seed extract: having a potential health benefits.Journal of food science and technology · 2020
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fatemeh HosseinzadehDepartment of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Moosa SalehiDepartment of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Nader TanidehStem Cell Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Davood MehrabaniStem Cell Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Azadeh SayarifardCenter for Academic and Health Policy, Tehran University of Medical Sciences, Tehran, Iran.
Anahita SedighiDepartment of Cellular and Molecular Biology, Pharmaceutical Science Branch, Islamic Azad University, Tehran, Iran.
Shiraz University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory bowel diseases contain two digestive system diseases, ulcerative colitis (UC) and Crohn's disease with unclear causes. The aim of present study was to investigate the therapeutic effects of administration of the Sesame oil (SO) and grape seed oil (GSO) as enema route in rats suffering from experimental acetic acid induced UC.

methodsEighty male rats were randomly allocated into 8 equal groups as health control (HC

resultsNo significant changes were detected in weight in neither groups on day 0 nor at the end of study. No beneficial effects were seen for all treatments regarding healing process and the decrease in inflammation. Between treatment groups, the lowest MDA (7.40±0.98 U/ml), CRP (83.20±10.01 mg/l) and IL-6 levels (130.86±10.70 mU/ml) and highest TAC (1.91±0.43 mmol/l) belonged to GSO group.

conclusionGSO enema alone can be considered as a treatment of choice for UC due to its antioxidant properties.

Indexed as

EnemaGrape seed oilSesame oilUlcerative colitis

Identifiers

PMID28713708
PMCPMC5506352
OpenAlexW2733759524

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.