ArticlePeerJ2017
Methodological considerations in assessment of language lateralisation with fMRI: a systematic review.
Article in PeerJ, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A quantitative approach for measuring laterality in clinical fMRI for preoperative language mapping.Neuroradiology · 2021Pooled it
- Uncovering Individual Language Vulnerability in Epilepsy Through Functional Connectivity Laterality.Clinical neuroradiology · 2026Article
- Language laterality and cognitive skills: does anatomy matter?Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Does white matter structure relate to hemispheric language lateralization? A systematic review.Brain communications · 2026Review
- Associations between fMRI signal amplitude, hemispheric asymmetry, and task performance.Communications biology · 2025Article
- Individualized Functional and Structural Language Lateralities in Temporal Lobe Epilepsy and Their Impact on Memory.Human brain mapping · 2025Article
- Functional divergence between the two cerebral hemispheres contributes to human fluid intelligence.Communications biology · 2025Article
- Cerebral Lateralization During Handwritten and Typed Word Generation: A Functional Transcranial Doppler Ultrasound Study in Left-Handers and Right-Handers.The European journal of neuroscience · 2025Observational
- Revisiting atypical language lateralization in dyslexia.Brain communications · 2025Article
- Exploring the Relationship Between White Matter Tracts and Resting-State Functional Language Lateralization Index.Neurobiology of language (Cambridge, Mass.) · 2025Article
- Unveiling the neuroplastic capacity of the bilingual brain: insights from healthy and pathological individuals.Brain structure & function · 2024Article
- Widespread asymmetries of amygdala nuclei predict auditory verbal hallucinations in schizophrenia.BMC psychiatry · 2024Article
- Article
- Variability in Hemispheric Functional Segregation Phenotypes: A Review and General Mechanistic Model.Neuropsychology review · 2024Review
- No evidence of altered language laterality in people who stutter across different brain imaging studies of speech and language.Brain communications · 2024Article
- Approaches to Measuring Language Lateralisation: An Exploratory Study Comparing Two fMRI Methods and Functional Transcranial Doppler Ultrasound.Neurobiology of language (Cambridge, Mass.) · 2024Article
- A systematic review of neuroimaging approaches to mapping language in individuals.Journal of neurolinguistics · 2023Article
- Beyond Broca's and Wernicke's: Functional Mapping of Ancillary Language Centers Prior to Brain Tumor Surgery.Tomography (Ann Arbor, Mich.) · 2023Review
- Occupation-modulated language networks and its lateralization: A resting-state fMRI study of seafarers.Frontiers in human neuroscience · 2023Article
- Analysis of distributions reveals real differences on dichotic listening scores between left- and right-handers.Cerebral cortex communications · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The involvement of the right and left hemispheres in mediating language functions has been measured in a variety of ways over the centuries since the relative dominance of the left hemisphere was first known. Functional magnetic resonance imaging (fMRI) presents a useful non-invasive method of assessing lateralisation that is being increasingly used in clinical practice and research. However, the methods used in the fMRI laterality literature currently are highly variable, making systematic comparisons across studies difficult. Here we consider the different methods of quantifying and classifying laterality that have been used in fMRI studies since 2000, with the aim of determining which give the most robust and reliable measurement. Recommendations are made with a view to informing future research to increase standardisation in fMRI laterality protocols. In particular, the findings reinforce the importance of threshold-independent methods for calculating laterality indices, and the benefits of assessing heterogeneity of language laterality across multiple regions of interest and tasks. This systematic review was registered as a protocol on Open Science Framework: https://osf.io/hyvc4/.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.