ReviewJournal of pregnancy2017
Small Molecule, Big Prospects: MicroRNA in Pregnancy and Its Complications.
Review in Journal of pregnancy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
74 citing papers in PubMed, 2 syntheses or guidelines pooled it, 117 citations in OpenAlex.
- Pooled it
- Circulating Nucleic Acids in Maternal Plasma and Serum in Pregnancy Complications: Are They Really Useful in Clinical Practice? A Systematic Review.Molecular diagnosis & therapy · 2020Pooled it
- Review
- PCYT1B-Targeting miRNAs as Potential Biomarkers for Placental Diseases.International journal of molecular sciences · 2026Article
- Amniotic Mesenchymal Stromal/Stem Cell-Derived Extracellular Vesicles for Equine Chronic Degenerative Endometritis Treatment.Veterinary medicine and science · 2026Article
- Social Determinants of Health Patterns in Children with Severe Disease Due to SARS-CoV-2 Infection-An Exploratory Approach.Children (Basel, Switzerland) · 2025Article
- First trimester circulating miR-208b-3p and miR-26a-1-3p are relevant to the prediction of gestational hypertension.BMC pregnancy and childbirth · 2025Article
- RNA Sequencing Reveals the Involvement of Serum Exosomal miRNAs in Early Pregnancy in Cattle.Animals : an open access journal from MDPI · 2024Article
- MicroRNAs in the Pathogenesis of Preeclampsia-A Case-Control In Silico Analysis.Current issues in molecular biology · 2024Article
- Value of Non-Coding RNA Expression in Biofluids to Identify Patients at Low Risk of Pathologies Associated with Pregnancy.Diagnostics (Basel, Switzerland) · 2024Review
- miRNA-protein-metabolite interaction network reveals the regulatory network and players of pregnancy regulation in dairy cows.Frontiers in cell and developmental biology · 2024Review
- LncRNA HCG27 Promotes Glucose Uptake Ability of HUVECs by MiR-378a-3p/MAPK1 Pathway.Current medical science · 2023Article
- MicroRNAs Associated with the Pathophysiological Mechanisms of Gestational Diabetes Mellitus: A Systematic Review for Building a Panel of miRNAs.Journal of personalized medicine · 2023Review
- Gestational Viral Infections: Role of Host Immune System.Microorganisms · 2023Review
- Exploring the potential of microRNA as a diagnostic tool for gestational diabetes.Journal of translational medicine · 2023Review
- Association of miR-196a2 and miR-27a polymorphisms with gestational diabetes mellitus susceptibility in a Chinese population.Frontiers in endocrinology · 2023Article
- The Role of Cluster C19MC in Pre-Eclampsia Development.International journal of molecular sciences · 2022Review
- Association of miRNA targetome variants in LAMC1 and GNB3 genes with colorectal cancer and obesity.Cancer medicine · 2022Article
- Impairment of Decidualization of Endometrial Stromal Cells by hsa-miR-375 Through NOX4 Targeting.Reproductive sciences (Thousand Oaks, Calif.) · 2022Article
- MicroRNA-185-5p: a marker of brain-sparing in foetuses with late-onset growth restriction.Epigenetics · 2022Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
MicroRNAs are small, noncoding RNA molecules that regulate target gene expression in the posttranscriptional level. Unlike siRNA, microRNAs are "fine-tuners" rather than "switches" in the regulation of gene expression; thus they play key roles in maintaining tissue homeostasis. The aberrant microRNA expression is implicated in the disease process. To date, numerous studies have demonstrated the regulatory roles of microRNAs in various pathophysiological conditions. In contrast, the study of microRNA in pregnancy and its associated complications, such as preeclampsia (PE), fetal growth restriction (FGR), and preterm labor, is a young field. Over the last decade, the knowledge of pregnancy-related microRNAs has increased and the molecular mechanisms by which microRNAs regulate pregnancy or its associated complications are emerging. In this review, we focus on the recent advances in the research of pregnancy-related microRNAs, especially their function in pregnancy-associated complications and the potential clinical applications. Here microRNAs that associate with pregnancy are classified as placenta-specific, placenta-associated, placenta-derived circulating, and uterine microRNA according to their localization and origin. MicroRNAs offer a great potential for developing diagnostic and therapeutic targets in pregnancy-related disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.