ArticleBJPsych open2017
Formal thought disorder in people at ultra-high risk of psychosis.
Article in BJPsych open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 32 citations in OpenAlex.
- Subjective language disturbances in young patients at ultra-high risk for psychosis (UHR): what relevance for clinical prognosis? A 2-year follow-up study.European archives of psychiatry and clinical neuroscience · 2026Article
- Diagnostic Utility of Formal Thought Disorder Between Affective and Non-Affective Psychosis: A Machine Learning Approach.The Psychiatric quarterly · 2026Article
- The effect of impoverishment of thought in early psychosis: Influence on suicide risk via depression and aggression.Dusunen adam : Bakirkoy Ruh ve Sinir Hastaliklari Hastanesi yayin organi · 2025Article
- Leveraging computational linguistics and machine learning for detection of ultra-high risk of mental health disorders in youths.Schizophrenia (Heidelberg, Germany) · 2025Article
- Towards a scalable approach to assess speech organization across the psychosis-spectrum -online assessment in conjunction with automated transcription and extraction of speech measures.Translational psychiatry · 2024Article
- Semantic Speech Networks Linked to Formal Thought Disorder in Early Psychosis.Schizophrenia bulletin · 2023Article
- Automated analysis of speech as a marker of sub-clinical psychotic experiences.Frontiers in psychiatry · 2023Review
- Association of cortical thickness and cognition with schizophrenia treatment resistance.Psychiatry and clinical neurosciences · 2023Article
- Thought Disorder as a Neglected Dimension in Schizophrenia.Alpha psychiatry · 2022Review
- Natural Language Processing markers in first episode psychosis and people at clinical high-risk.Translational psychiatry · 2021Article
- The cognitive aspect of formal thought disorder and its relationship with global social functioning and the quality of life in schizophrenia.Social psychiatry and psychiatric epidemiology · 2021Article
- White Matter in Schizophrenia Treatment Resistance.The American journal of psychiatry · 2019Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFormal thought disorder is a cardinal feature of psychosis. However, the extent to which formal thought disorder is evident in ultra-high-risk individuals and whether it is linked to the progression to psychosis remains unclear.
aimsExamine the severity of formal thought disorder in ultra-high-risk participants and its association with future psychosis.
methodThe Thought and Language Index (TLI) was used to assess 24 ultra-high-risk participants, 16 people with first-episode psychosis and 13 healthy controls. Ultra-high-risk individuals were followed up for a mean duration of 7 years (s.d.=1.5) to determine the relationship between formal thought disorder at baseline and transition to psychosis.
resultsTLI scores were significantly greater in the ultra-high-risk group compared with the healthy control group (effect size (ES)=1.2), but lower than in people with first-episode psychosis (ES=0.8). Total and negative TLI scores were higher in ultra-high-risk individuals who developed psychosis, but this was not significant. Combining negative TLI scores with attenuated psychotic symptoms and basic symptoms predicted transition to psychosis (
conclusionsTLI is beneficial in evaluating formal thought disorder in ultra-high-risk participants, and complements existing instruments for the evaluation of psychopathology in this group. DECLARATION OF INTERESTS: None. COPYRIGHT AND USAGE: © The Royal College of Psychiatrists 2017. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) license.
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