Evidence map›Paper›PMID 28713364›Full record

ArticleFrontiers in immunology2017

Immunomodulatory Activities of a Fungal Protein Extracted from

Chen Diling, Zheng Chaoqun, Yang Jian, Li Jian, Su Jiyan, Xie Yizhen, Lai Guoxiao

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04821258 (Double-blind Randomized Clinical Trial to Evaluate the Effect of the Nutraceutical "MICODIGEST 2.0" on the Complications After Surgery With Curative Intent for Colorectal Cancer), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04821258 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Double-blind Randomized Clinical Trial to Evaluate the Effect of the Nutraceutical "MICODIGEST 2.0" on the Complications After Surgery With Curative Intent for Colorectal Cancer

TypeinterventionalSponsorFundacin Biomedica Galicia SurRan2021 to 2022Enrolled144ConditionsColorectal Cancer, Surgery--ComplicationsArmsMICODIGEST 2.0 supplement, Placebo supplement
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Foods (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Article
  8. Coffee withPharmaceuticals (Basel, Switzerland) · 2024
    Article
  9. Review
  10. World journal of gastroenterology · 2023
    Review
  11. Journal of fungi (Basel, Switzerland) · 2023
    Review
  12. Frontiers in immunology · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Chen DilingState Key Laboratory of Applied Microbiology South China, Guangdong Institute of Microbiology, Guangzhou, China.
Zheng ChaoqunState Key Laboratory of Applied Microbiology South China, Guangdong Institute of Microbiology, Guangzhou, China.
Yang JianState Key Laboratory of Applied Microbiology South China, Guangdong Institute of Microbiology, Guangzhou, China.
Li JianState Key Laboratory of Applied Microbiology South China, Guangdong Institute of Microbiology, Guangzhou, China.
Su JiyanState Key Laboratory of Applied Microbiology South China, Guangdong Institute of Microbiology, Guangzhou, China.
Xie YizhenState Key Laboratory of Applied Microbiology South China, Guangdong Institute of Microbiology, Guangzhou, China.
Lai GuoxiaoState Key Laboratory of Applied Microbiology South China, Guangdong Institute of Microbiology, Guangzhou, China.
Institute of Microbiology · CNGuangxi University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A single-band protein (HEP3) was isolated from

Indexed as

anti-inflammationfunctional food ingredientfungal immunomodulatory proteingut microbiotaHericium erinaceusimmunotherapy

Identifiers

PMID28713364
PMCPMC5492111
OpenAlexW2624433117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.