Evidence map›Paper›PMID 28713342›Full record

ArticleFrontiers in microbiology2017

NF-κBp50 and HDAC1 Interaction Is Implicated in the Host Tolerance to Infection Mediated by the Bacterial Quorum Sensing Signal 2-Aminoacetophenone.

Arunava Bandyopadhaya, Amy Tsurumi, Laurence G Rahme

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Effects ofFrontiers in microbiology · 2026
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  4. Review
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  6. Frontiers in immunology · 2025
    Review
  7. Revealing the impact ofFrontiers in immunology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. mFrontiers in immunology · 2021
    Article
  12. [Advances in oral bacteria influencing host epigenetic regulation].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2020
    Review
  13. Article
  14. Translational perioperative and pain medicine · 2020
    Article
  15. Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Arunava BandyopadhayaDepartment of Surgery, Massachusetts General Hospital and Harvard Medical School, BostonMA, United States.
Amy TsurumiDepartment of Surgery, Massachusetts General Hospital and Harvard Medical School, BostonMA, United States.
Laurence G RahmeDepartment of Surgery, Massachusetts General Hospital and Harvard Medical School, BostonMA, United States.
Harvard University · USMassachusetts General Hospital · US

Funding

Molecular and Metabolic inter-kingdom actions of a bacterial quorum sensing signal in promotion of host tolerance/resilience.R01AI134857 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RAHME, LAURENCE G · 2018 to 2022
$3.4M
Interruption of Signaling-Mediated Bacterial Persistent InfectionsR33AI105902 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI RAHME, LAURENCE G · 2015 to 2017
$1.8M
NIAID NIH HHS R01 AI134857NIAID NIH HHS R33 AI105902
6 · The paper itself

Abstract

Some bacterial quorum sensing (QS) small molecules are important mediators of inter-kingdom signaling and impact host immunity. The QS regulated small volatile molecule 2-aminoacetophenone (2-AA), which has been proposed as a biomarker of

Indexed as

2-aminoacetophenoneCBP/p300HDAC1inflammatory cytokinesNF-κBquorum sensing

Identifiers

PMID28713342
PMCPMC5492500
OpenAlexW2725465023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.