ReviewFrontiers in psychiatry2017
An Expanding World of Novel Psychoactive Substances: Opioids.
Review in Frontiers in psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pharmacotherapy of Patients Taking New Psychoactive Substances: A Systematic Review and Analysis of Case Reports.Frontiers in psychiatry · 2021Pooled it
- Discriminative stimulus, rewarding, and reinforcing effects of 4-Fluoroethylphenidate in rodents.Psychopharmacology · 2026Article
- Development and Validation of a Gas Chromatography-Mass Spectrometry Method for the Determination of Fentanyl and Butyryl Fentanyl in Oral Fluid.Analytical science advances · 2025Article
- New Synthetic Compounds with Psychoactive Action-Preliminary Results Among Primary and High School Students on the Territory of Novi Sad.Medicines (Basel, Switzerland) · 2025Article
- In vitro metabolism of seven arolyl-derived fentanyl-type new psychoactive substances.Archives of toxicology · 2025Article
- A comparative examination of morphine and fentanyl: unravelling the differential impacts on breathing and airway stability.The Journal of physiology · 2023Article
- Article
- Comparative analysis of the metabolites and biotransformation pathways of fentanyl in the liver and brain of zebrafish.Frontiers in pharmacology · 2023Article
- The Genotoxicity of Acrylfentanyl, Ocfentanyl and Furanylfentanyl Raises the Concern of Long-Term Consequences.International journal of molecular sciences · 2022Article
- Attenuated total reflection-Fourier transform infrared spectroscopy: a universal analytical technique with promising applications in forensic analyses.International journal of legal medicine · 2022Review
- Reports of Adverse Events Associated with Use of Novel Psychoactive Substances, 2017-2020: A Review.Journal of analytical toxicology · 2022Review
- An Update on the Implications of New Psychoactive Substances in Public Health.International journal of environmental research and public health · 2022Review
- Developments in high-resolution mass spectrometric analyses of new psychoactive substances.Archives of toxicology · 2022Review
- A new quantitative drug checking technology for harm reduction: Pilot study in Vancouver, Canada using paper spray mass spectrometry.Drug and alcohol review · 2022Article
- Knowledge and Use of Novel Psychoactive Substances in an Italian Sample with Substance Use Disorders.International journal of environmental research and public health · 2022Article
- Blood concentrations of new synthetic opioids.International journal of legal medicine · 2022Review
- Synthetic opioids: a review and clinical update.Therapeutic advances in psychopharmacology · 2022Review
- Respiratory depressant effects of fentanyl analogs are opioid receptor-mediated.Biochemical pharmacology · 2022Article
- Antinociceptive and Discriminative Stimulus Effects of Six Novel Psychoactive Opioid Substances in Male Rats.The Journal of pharmacology and experimental therapeutics · 2021Article
- Seizures of New Psychoactive Substances on the Italian territory during the COVID-19 pandemic.Forensic science international · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The abuse of novel psychoactive substances (NPS) has been increasing dramatically worldwide since late 2000s. By the end of 2015, more than 560 NPS had been reported to the European Monitoring Centre for Drugs and Drug Addiction. Although the most popular compounds are synthetic cannabinoids and psychostimulatory derivatives of cathinone (so-called β-keto-amphetamines), novel synthetic opioids have recently emerged on the recreational drug market. They include fentanyl (a potent narcotic analgesic) and its analogs (e.g., acetylfentanyl, acryloylfentanyl, carfentanil, α-methylfentanyl, 3-methylfentanyl, furanylfentanyl, 4-fluorobutyrylfentanyl, 4-methoxybutyrylfentanyl, 4-chloroisobutyrylfentanyl, 4-fluoroisobutyrylfentanyl, tetrahydrofuranylfentanyl, cyclopentylfentanyl, and ocfentanil) and compounds with different chemical structures, such as AH-7921, MT-45, and U-47700. This survey provides an overview of the pharmacological properties, pattern of use, and desired and unwanted effects of the above-listed novel opioids. Special emphasis is given to cases of non-fatal and lethal intoxication involving these compounds.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.