Evidence map›Paper›PMID 28713287›Full record

ArticleFrontiers in physiology2017

Vitamin A Affects Flatfish Development in a Thyroid Hormone Signaling and Metamorphic Stage Dependent Manner.

Ignacio Fernández, Juan B Ortiz-Delgado, Maria J Darias, Francisco Hontoria, Karl B Andree, Manuel Manchado, Carmen Sarasquete, Enric Gisbert

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. New Insights on Vitamin K Metabolism in Senegalese sole (International journal of molecular sciences · 2020
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Ignacio FernándezCentro de Ciências do Mar (CCMAR), Universidade do AlgarveFaro, Portugal.
Juan B Ortiz-DelgadoInstituto de Ciencias Marinas de Andalucía (CSIC)Cádiz, Spain.
Maria J DariasUnité Mixte de Recherche Biologie des Organismes et Ecosystèmes Aquatiques, Institut de Recherche Pour le DéveloppementMontpellier, France.
Francisco HontoriaInstituto de Ciencias Marinas de Andalucía (CSIC)Torre de la Sal, Castellón, Spain.
Karl B AndreeUnitat de Cultius Experimentals, Centre de Sant Carles de la Ràpita, Institute for Research and Technology in Food and AgricultureSant Carles de la Ràpita, Spain.
Manuel ManchadoIFAPA Centro "El Toruño," Junta de Andalucía, El Puerto de Santa MariaCádiz, Spain.
Carmen SarasqueteInstituto de Ciencias Marinas de Andalucía (CSIC)Cádiz, Spain.
Enric GisbertUnitat de Cultius Experimentals, Centre de Sant Carles de la Ràpita, Institute for Research and Technology in Food and AgricultureSant Carles de la Ràpita, Spain.
Institute for Research and Technology in Food and Agriculture · ESInstituto de Ciencias Marinas de Andalucía · ESBiologie des Organismes et Écosystèmes Aquatiques · FRInstituto de Acuicultura Torre de la Sal · ESJunta de Andalucía · ESUniversity of Algarve · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin A (VA) and retinoid derivatives are known morphogens controlling vertebrate development. Despite the research effort conducted during the last decade, the precise mechanism of how VA induces post-natal bone changes, and particularly those operating through crosstalk with the thyroid hormones (THs) remain to be fully understood. Since effects and mechanisms seem to be dose and time-dependent, flatfish are an interesting study model as they undergo a characteristic process of metamorphosis driven by THs that can be followed by external appearance. Here, we studied the effects of VA imbalance that might determine Senegalese sole (

Indexed as

flatfishnuclear receptorsossificationSenegalese soleskeletogenesisSolea senegalensisthyroidal folliclesvitamin A

Identifiers

PMID28713287
PMCPMC5492123
OpenAlexW2725323425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.