Evidence map›Paper›PMID 28713241›Full record

ArticleFrontiers in molecular neuroscience2017

Cold Temperature Encoding by Cutaneous TRPA1 and TRPM8-Carrying Fibers in the Mouse.

Zoltan Winter, Philipp Gruschwitz, Stephanie Eger, Filip Touska, Katharina Zimmermann

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Ion channels of cold transduction and transmission.The Journal of general physiology · 2024
    Review
  6. Thermosensing ability of TRPC5: current knowledge and unsettled questions.The journal of physiological sciences : JPS · 2024
    Review
  7. KCNQ1 is an essential mediator of the sex-dependent perception of moderate cold temperatures.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Piezo2 Mediates Low-Threshold Mechanically Evoked Pain in the Cornea.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. The Immunosuppressant Macrolide Tacrolimus Activates Cold-Sensing TRPM8 Channels.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zoltan WinterDepartment of Anesthesiology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-NürnbergErlangen, Germany.
Philipp GruschwitzDepartment of Anesthesiology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-NürnbergErlangen, Germany.
Stephanie EgerDepartment of Anesthesiology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-NürnbergErlangen, Germany.
Filip TouskaDepartment of Anesthesiology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-NürnbergErlangen, Germany.
Katharina ZimmermannDepartment of Anesthesiology, University Hospital Erlangen, Friedrich-Alexander-University Erlangen-NürnbergErlangen, Germany.
Universitätsklinikum Erlangen · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous research identified TRPM8 and TRPA1 cold transducers with separate functions, one being functional in the non-noxious range and the second one being a nociceptive transducer. TRPM8-deficient mice present overt deficits in the detection of environmental cool, but not a lack of cold avoidance and TRPA1-deficient mice show clear deficits in some cold nocifensive assays. The extent of TRPA1's contribution to cold sensing

Indexed as

129S1/SvImJC57BL/6Jcold avoidancecold transductionnociceptorstrain differencethermal preference behaviorthermoreceptor

Identifiers

PMID28713241
PMCPMC5492152
OpenAlexW2724579712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.