ArticleEuropean polymer journal2017
POxylation as an alternative stealth coating for biomedical applications.
Article in European polymer journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 106 citations in OpenAlex.
- Antibody-mediated recognition of chiral poly(2-oxazoline) nanorods driven by enantioselectivity.Chemical science · 2026Article
- Circular-by-Design Zwitterionic Polyglycerol-Polyoxazoline-Lysine Pseudodendrimers as Multifunctional Antibacterial and Anticancer Drug Delivery Platforms.Biomacromolecules · 2026Article
- Siloxane-tethered poly(2-ethyl-2-oxazoline) as surface modifying additives for anti-fouling silicones.European polymer journal · 2026Article
- Virus-like particles based on plant viruses and bacteriophages: emerging strategies for the delivery of nucleic acid therapeutics.Chemical science · 2026Review
- Biodegradable Polyglycerols Combining Antioxidant Activity and Sulfation-Induced Complement Inhibition.Biomacromolecules · 2026Article
- PEGylation technology: addressing concerns, moving forward.Drug delivery · 2025Review
- Recent advances in smart gold nanoparticles for photothermal therapy.Nanomedicine (London, England) · 2025Review
- Species differences in opsonization and phagocyte recognition of preclinical poly-2-alkyl-2-oxazoline-coated nanoparticles.Nature communications · 2025Article
- Chromenylium Star Polymers: Merging Water Solubility and Stealth Properties with Shortwave Infrared Emissive Fluorophores.ACS central science · 2025Article
- Organocyclophosphazenes and Materials Based on Them for Pharmaceuticals and Biomedicine.Biomolecules · 2025Review
- Solid Lipid Nanoparticles Coated with Glucosylated poly(2-oxazoline)s: A Supramolecular Toolbox Approach.Biomacromolecules · 2025Article
- Tailoring Gene Transfer Efficacy through the Arrangement of Cationic and Anionic Blocks in Triblock Copolymer Micelles.ACS macro letters · 2024Article
- Knowledge-Based Design of Multifunctional Polymeric Nanoparticles.Handbook of experimental pharmacology · 2024Article
- Polyoxazoline-Based Nanovaccine Synergizes with Tumor-Associated Macrophage Targeting and Anti-PD-1 Immunotherapy against Solid Tumors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Polymer-based drug delivery systems under investigation for enzyme replacement and other therapies of lysosomal storage disorders.Advanced drug delivery reviews · 2023Review
- Polymeric Gel Systems Cytotoxicity and Drug Release as Key Features for their Effective Application in Various Fields of Addressed Pharmaceuticals Delivery.Pharmaceutics · 2023Review
- Conformational Parameters and Hydrodynamic Behavior of Poly(2-Methyl-2-Oxazoline) in a Broad Molar Mass Range.Polymers · 2023Article
- Inulin-g-poly-D,L-lactide, a sustainable amphiphilic copolymer for nano-therapeutics.Drug delivery and translational research · 2022Article
- PEG: Will It Come Back to You? Polyethelyne Glycol Immunogenicity, COVID Vaccines, and the Case for New PEG Derivatives and Alternatives.Frontiers in bioengineering and biotechnology · 2022Article
- Functional Polyglycidol-Based Block Copolymers for DNA Complexation.International journal of molecular sciences · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Polyethylene glycol (PEG) polymers are currently used in a variety of medical formulations to reduce toxicity, minimize immune interactions and improve pharmacokinetics. Despite its widespread use however, the presence of anti-PEG antibodies indicates that this polymer has the potential to be immunogenic and antigenic. Here we present an alternative polymer, poly(2-oxazoline) (POx) for stealth applications, specifically shielding of a proteinaceous nanoparticle from recognition by the immune system. Tobacco mosaic virus (TMV) was used as our testbed due to its potential for use as a nanocarrier for drug delivery and molecular imaging applications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.