Evidence map›Paper›PMID 28712640›Full record

ArticleBiophysical journal2017

Resident Calmodulin Primes NMDA Receptors for Ca

Gary J Iacobucci, Gabriela K Popescu

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. The positive allosteric modulator GNE-9278 increases gating, conductance, and CaNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. d-Serine Inhibits Non-ionotropic NMDA Receptor Signaling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  7. Review
  8. Review
  9. Review
  10. Estimating the CaMethods in molecular biology (Clifton, N.J.) · 2024
    Article
  11. CaNature plants · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gary J IacobucciDepartment of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York. Electronic address: garyiaco@buffalo.edu.
Gabriela K PopescuDepartment of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, New York. Electronic address: popescu@buffalo.edu.
University at Buffalo, State University of New York · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Probing allosteric surfaces of NMDA receptorsR01NS052669 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI POPESCU, GABRIELA K · 2006 to 2015
$3.4M
Molecular Physiology of NMDA ReceptorsR35NS132248 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Gabriela K Popescu · 2023 to 2026
$2.3M
Gating Mechanism of NMDA ReceptorsR01NS108750 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI POPESCU, GABRIELA K · 2019 to 2023
$1.5M
Permeation Mechanisms in NMDA receptorsR01NS097016 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI POPESCU, GABRIELA K · 2016 to 2019
$1.4M
Mechanical Activation of NMDA ReceptorsR21NS098385 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI POPESCU, GABRIELA K · 2016 to 2017
$439k
NCATS NIH HHS UL1 TR001412NINDS NIH HHS R01 NS052669NINDS NIH HHS R01 NS097016NINDS NIH HHS R01 NS108750NINDS NIH HHS R21 NS098385NINDS NIH HHS R35 NS132248
6 · The paper itself

Abstract

N-methyl-d-aspartate (NMDA) receptors are glutamate- and glycine-gated channels that flux Na

Indexed as

AnimalsApoproteinsCalciumCalmodulinHEK293 CellsHippocampusHumansIntracellular SpaceNeuronsPorosityProtein DomainsRatsReceptors, N-Methyl-D-AspartateSynaptic TransmissionApoproteinsCalciumCalmodulinReceptors, N-Methyl-D-Aspartate

Identifiers

PMID28712640
PMCPMC5700250
OpenAlexW2735771895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.