Observational studyValue in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
Estimating Health-State Utility Values in Kidney Transplant Recipients and Waiting-List Patients Using the EQ-5D-5L.
Observational study in Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06396702 (Emotion And Symptom-focused Engagement), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Emotion And Symptom-focused Engagement (EASE) Intervention for the Management of Emotional and Physical Symptoms Among Solid Organ Transplant Recipients-pilot Study
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Biomarkers for assessing acute kidney injury for people who are being considered for admission to critical care: a systematic review and cost-effectiveness analysis.Health technology assessment (Winchester, England) · 2022Pooled it
- Predicting EQ-5D-3L utility values from clinical data in a prospective cohort of kidney transplant recipients.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Observational
- Economic evaluation of automated peritoneal dialysis among pediatric patients with end state kidney diseases in Thailand.Scientific reports · 2025Article
- Cost-effectiveness of population-based screening for chronic kidney disease among the general population and adults with diabetes in China: a modelling study.The Lancet regional health. Western Pacific · 2025Article
- Return-to-work in lung transplant recipients: an Australian perspective.Internal medicine journal · 2025Article
- Validation of a Core Patient-Reported Outcome Measure for Life Participation in Kidney Transplant Recipients: the SONG Life Participation Instrument.Kidney international reports · 2024Article
- Management strategies and outcomes in renal transplant recipients recovering from COVID-19: A retrospective, multicentre, cohort study.EClinicalMedicine · 2022Article
- Cost-Utility Analysis of Dapagliflozin as an Add-on to Standard of Care for Patients with Chronic Kidney Disease in Thailand.Advances in therapy · 2022Article
- Optimising Access Surgery in Senior Haemodialysis Patients (OASIS): study protocol for a multicentre randomised controlled trial.BMJ open · 2022Article
- Health-related quality of life, uncertainty and coping strategies in solid organ transplant recipients during shielding for the COVID-19 pandemic.Transplant international : official journal of the European Society for Organ Transplantation · 2021Article
- Cost-Utility Analysis of Dapagliflozin as an Add-On to Standard Treatment for Patients with Type 2 Diabetes and High Risk of Cardiovascular Disease in Thailand.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2021Article
- Equity-Efficiency Trade-offs Associated With Alternative Approaches to Deceased Donor Kidney Allocation: A Patient-level Simulation.Transplantation · 2020Article
- Frailty and the Kidney Transplant Wait List: Protocol for a Multicenter Prospective Study.Canadian journal of kidney health and disease · 2020Article
- The impact of chronic kidney disease on developed countries from a health economics perspective: A systematic scoping review.PloS one · 2020Article
- Association of Kidney Transplant Center Volume With 3-Year Clinical Outcomes.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2019Article
- Health-related quality of life and mortality in patients with pulmonary embolism: a prospective cohort study in seven European countries.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
- Benefit finding in renal transplantation and its association with psychological and clinical correlates: A prospective study.British journal of health psychology · 2019Article
- Crisis Preparedness by Simulating Quality-Adjusted Life-Year Loss in Patients with End-Stage Renal Disease due to Kidney Transplantation Suspensions.MDM policy & practiceArticle
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
objectivesTo report health-state utility values measured using the five-level EuroQol five-dimensional questionnaire (EQ-5D-5L) in a large sample of patients with end-stage renal disease and to explore how these values vary in relation to patient characteristics and treatment factors.
methodsAs part of the prospective observational study entitled "Access to Transplantation and Transplant Outcome Measures," we captured information on patient characteristics and treatment factors in a cohort of incident kidney transplant recipients and a cohort of prevalent patients on the transplant waiting list in the United Kingdom. We assessed patients' health status using the EQ-5D-5L and conducted multivariable regression analyses of index scores.
resultsEQ-5D-5L responses were available for 512 transplant recipients and 1704 waiting-list patients. Mean index scores were higher in transplant recipients at 6 months after transplant surgery (0.83) compared with patients on the waiting list (0.77). In combined regression analyses, a primary renal diagnosis of diabetes was associated with the largest decrement in utility scores. When separate regression models were fitted to each cohort, female gender and Asian ethnicity were associated with lower utility scores among waiting-list patients but not among transplant recipients. Among waiting-list patients, longer time spent on dialysis was also associated with poorer utility scores. When comorbidities were included, the presence of mental illness resulted in a utility decrement of 0.12 in both cohorts.
conclusionsThis study provides new insights into variations in health-state utility values from a single source that can be used to inform cost-effectiveness evaluations in patients with end-stage renal disease.
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