Evidence map›Paper›PMID 28712421›Full record

ArticleJournal of psychosomatic research2017

Number of recent stressful life events and incident cardiovascular disease: Moderation by lifetime depressive disorder.

Jessica Berntson, Jay S Patel, Jesse C Stewart

Open access · greenAbstract read
In one paragraph

Article in Journal of psychosomatic research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jessica BerntsonDepartment of Psychology, Indiana University-Purdue University Indianapolis (IUPUI), Indianapolis, United States.
Jay S PatelDepartment of Psychology, Indiana University-Purdue University Indianapolis (IUPUI), Indianapolis, United States.
Jesse C StewartDepartment of Psychology, Indiana University-Purdue University Indianapolis (IUPUI), Indianapolis, United States. Electronic address: jstew@iupui.edu.
Indiana University – Purdue University Indianapolis · US

Funding

Modernized Collaborative Care to Reduce the Excess CVD Risk of Depressed PatientsR01HL122245 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI STEWART, JESSE C · 2015 to 2019
$2.6M
NHLBI NIH HHS R01 HL122245
6 · The paper itself

Abstract

objectiveWe investigated whether number of recent stressful life events is associated with incident cardiovascular disease (CVD) and whether this relationship is stronger in adults with a history of clinical depression.

methodsProspective data from 28,583 U.S. adults (mean age=45years) initially free of CVD who participated in Waves 1 (2001-2002) and 2 (2004-2005) of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) were examined. Number of past-year stressful life events (Wave 1), lifetime depressive disorder (Wave 1), and incident CVD (Wave 2) were determined by structured interviews.

resultsThere were 1069 cases of incident CVD. Each additional stressful life event was associated with a 15% increased odds of incident CVD [Odds Ratio (OR)=1.15, 95% Confidence Interval (CI): 1.11, 1.19]. As hypothesized, a stressful life events by lifetime depressive disorder interaction was detected (P=0.003). Stratified analyses indicated that stressful life events had a stronger association with incident CVD among adults with (OR=1.18, 95% CI: 1.10, 1.27, n=4908) versus without (OR=1.10, 95% CI: 1.07, 1.14, n=23,675) a lifetime depressive disorder.

conclusionOur findings suggest that a greater number of recent stressful life events elevate the risk of new-onset CVD and that this risk is potentiated in adults with a history of clinical depression.

Indexed as

Life Change EventsCardiovascular DiseasesDepressive DisorderFemaleHumansMaleMiddle AgedProspective StudiesRisk FactorsCardiovascular diseasesDepressive disorderEpidemiologic studiesLife change eventsProspective studiesStress, psychological

Identifiers

PMID28712421
PMCPMC5558851
OpenAlexW2624829326

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.