Evidence map›Paper›PMID 28712385›Full record

ArticleEpidemiology and infection2017

Pregnant with HIV before age 25: data from a large national study in Italy, 2001-2016.

M Floridia, G Masuelli, E Tamburrini, I Cetin, G Liuzzi, P Martinelli, G Guaraldi, A Spinillo, A Vimercati, G Maso and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 2 countries.

M FloridiaNational Centre for Global Health, Istituto Superiore di Sanità,Rome,Italy.ORCID 0000-0003-3971-0141
G MasuelliDepartment of Obstetrics and Neonatology,Città della Salute e della Scienza Hospital, and University of Turin,Italy.
E TamburriniDepartment of Infectious Diseases,Catholic University,Rome,Italy.
I CetinDepartment of Obstetrics and Gynaecology,Luigi Sacco Hospital and University of Milan,Italy.
G LiuzziI.N.M.I. Lazzaro Spallanzani,Rome,Italy.
P MartinelliDepartment of Neurosciences,Reproductive and Dentistry Science, University Federico II,Naples,Italy.
G GuaraldiDepartment of Medical Specialties,Infectious Diseases Clinic,University of Modena and Reggio Emilia,Modena,Italy.
A SpinilloDepartment of Obstetrics and Gynaecology,IRCCS S. Matteo,Pavia,Italy.
A VimercatiDepartment of Obstetrics and Gynaecology,University of Bari,Italy.
G MasoInstitute for Maternal and Child Health, IRCCS Burlo Garofolo,Trieste,Italy.
C PinnettiI.N.M.I. Lazzaro Spallanzani,Rome,Italy.
V FrisinaDepartment of Obstetrics and Neonatology,Città della Salute e della Scienza Hospital, and University of Turin,Italy.
S DalzeroDepartment of Obstetrics and Gynaecology,DMSD San Paolo Hospital Medical School,University of Milan,Italy.
M RavizzaDepartment of Obstetrics and Gynaecology,DMSD San Paolo Hospital Medical School,University of Milan,Italy.
University of Milan · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITIstituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITFederico II University Hospital · ITIRCCS Materno Infantile Burlo Garofolo · ITIstituto Superiore di Sanità · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Bari Aldo Moro · ITUniversity of Modena and Reggio Emilia · ITUniversity of Pavia · IT

Funding

Wellcome Trust
6 · The paper itself

Abstract

Young pregnant women with HIV may be at significant risk of unplanned pregnancy, lower treatment coverage, and other adverse pregnancy outcomes. In a large cohort of pregnant women with HIV in Italy, among 2979 pregnancies followed in 2001-2016, 9·0% were in women <25 years, with a significant increase over time (2001-2005: 7·0%; 2006-2010: 9·1%; 2011-2016: 12·2%, P < 0·001). Younger women had a lower rate of planned pregnancy (23·2% vs. 37·7%, odds ratio (OR) 0·50, 95% confidence interval (CI) 0·36-0·69), were more frequently diagnosed with HIV in pregnancy (46·5% vs. 20·9%, OR 3·29, 95% CI 2·54-4·25), and, if already diagnosed with HIV before pregnancy, were less frequently on antiretroviral treatment at conception (<25 years: 56·3%; ⩾25 years: 69·0%, OR 0·58, 95% CI 0·41-0·81). During pregnancy, treatment coverage was almost universal in both age groups (98·5% vs. 99·3%), with no differences in rate of HIV viral suppression at third trimester and adverse pregnancy outcomes. The data show that young women represent a growing proportion of pregnant women with HIV, and are significantly more likely to have unplanned pregnancy, undiagnosed HIV infection, and lower treatment coverage at conception. During pregnancy, antiretroviral treatment, HIV suppression, and pregnancy outcomes are similar compared with older women. Earlier intervention strategies may provide additional benefits in the quality of care for women with HIV.

Indexed as

AdolescentCohort StudiesFemaleHIV InfectionsHumansItalyOdds RatioPregnancyYoung AdultAntiretroviral treatmentHIV diagnosisHIV testingpregnancywomen's health

Identifiers

PMID28712385
PMCPMC9148819
OpenAlexW2735978517

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.