Evidence map›Paper›PMID 28712062›Full record

ReviewMammalian genome : official journal of the International Mammalian Genome Society2017

Genome editing and genetic engineering in livestock for advancing agricultural and biomedical applications.

Bhanu P Telugu, Ki-Eun Park, Chi-Hun Park

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mammalian genome : official journal of the International Mammalian Genome Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Gene Editing for Enhanced Swine Production: Current Advances and Prospects.Animals : an open access journal from MDPI · 2025
    Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Improvements in pig agriculture through gene editing.CABI agriculture and bioscience · 2022
    Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Bhanu P TeluguAnimal and Avian Science, University of Maryland, Bhanu Telugu, 2121 ANSC Building, College Park, MD, 20742, USA. btelugu@umd.edu.
Ki-Eun ParkAnimal and Avian Science, University of Maryland, Bhanu Telugu, 2121 ANSC Building, College Park, MD, 20742, USA.
Chi-Hun ParkAnimal and Avian Science, University of Maryland, Bhanu Telugu, 2121 ANSC Building, College Park, MD, 20742, USA.
Beltsville Agricultural Research Center · USData Voice Exchange (United States) · USUniversity of Maryland, College Park · US

Funding

National Institute of Food and Agriculture 2015-67015-22845
6 · The paper itself

Abstract

Genetic modification of livestock has a longstanding and successful history, starting with domestication several thousand years ago. Modern animal breeding strategies predominantly based on marker-assisted and genomic selection, artificial insemination, and embryo transfer have led to significant improvement in the performance of domestic animals, and are the basis for regular supply of high quality animal derived food. However, the current strategy of breeding animals over multiple generations to introduce novel traits is not realistic in responding to the unprecedented challenges such as changing climate, pandemic diseases, and feeding an anticipated 3 billion increase in global population in the next three decades. Consequently, sophisticated genetic modifications that allow for seamless introgression of novel alleles or traits and introduction of precise modifications without affecting the overall genetic merit of the animal are required for addressing these pressing challenges. The requirement for precise modifications is especially important in the context of modeling human diseases for the development of therapeutic interventions. The animal science community envisions the genome editors as essential tools in addressing these critical priorities in agriculture and biomedicine, and for advancing livestock genetic engineering for agriculture, biomedical as well as "dual purpose" applications.

Indexed as

AgricultureBiomedical ResearchGene EditingGenetic EngineeringGenomeAnimalsAnimals, DomesticBreedingHumansLivestock

Identifiers

PMID28712062
OpenAlexW2734914051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.