Evidence map›Paper›PMID 28711602›Full record

ArticleRespiratory physiology & neurobiology2017

Contribution of 5-HT

Kun-Ze Lee, Elisa J Gonzalez-Rothi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory physiology & neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Circuit Reconstruction after Traumatic Spinal Cord Injury by Cellular and Pharmacological Approaches.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Kun-Ze LeeDepartment of Biological Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan; Center for Neuroscience, National Sun Yat-Sen University, Kaohsiung, Taiwan; Institute of Medical Science and Technology, National Sun Yat-Sen University, Kaohsiung, Taiwan; Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, Taiwan; Doctoral Degree Program in Marine Biotechnology, National Sun Yat-Sen University and Academia Sinica, Taiwan. Electronic address: kzlee@mail.nsysu.edu.tw.
Elisa J Gonzalez-RothiDepartment of Physical Therapy, University of Florida, Gainesville, FL, USA.
Kaohsiung Medical University · TWUniversity of Florida · US

Funding

Rehabilitation Research Career Development ProgramK12HD055929 · NICHD · UNIVERSITY OF TEXAS MED BR GALVESTON · PI BROWN, DAVID A · 2007 to 2021
$11.7M
NICHD NIH HHS K12 HD055929
6 · The paper itself

Abstract

Unilateral C2 spinal cord hemisection (C2Hx) interrupts bulbospinal respiratory pathways innervating ipsilateral phrenic motoneurons, resulting in cessation of ipsilateral diaphragm motor output. Plasticity within the spinal neural circuitry controlling the diaphragm can induce partial recovery of phrenic bursting which correlates with the time-dependent return of spinal serotonin (5-HT) immunoreactivity in the vicinity of phrenic motoneurons. The 5-HT

Indexed as

Administration, IntravenousAnimalsCervical CordChronic DiseaseDiaphragmDisease Models, AnimalElectromyographyFunctional LateralityKetanserinMalePhrenic NerveRats, Sprague-DawleyReceptor, Serotonin, 5-HT2ARecovery of FunctionRespirationSerotonin 5-HT2 Receptor AntagonistsKetanserinReceptor, Serotonin, 5-HT2ASerotonin 5-HT2 Receptor Antagonists5-HT5-HT(2A) receptorCervical spinal cord injuryDiaphragm

Identifiers

PMID28711602
PMCPMC5705015
OpenAlexW2735321577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.