Evidence map›Paper›PMID 28711456›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

A cross-sectional study assessing the pharyngeal carriage of Neisseria meningitidis in subjects aged 1-24 years in the city of Embu das Artes, São Paulo, Brazil.

Lily Yin Weckx, Rosana Fiorini Puccini, Antónia Machado, Maria Gisele Gonçalves, Suely Tuboi, Eliana de Barros, Raghavendra Devadiga, Eduardo Ortega-Barria, Romulo Colindres

Abstract read
In one paragraph

Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Carriage prevalence of Neisseria meningitidis in the Americas in the 21st century: a systematic review.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Pooled it
  2. Frontiers in cellular and infection microbiology · 2025
    Review
  3. Article
  4. Article
  5. Vaccination for meningococcal disease.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2022
    Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lily Yin WeckxUniversidade Federal de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil. Electronic address: lily.crie@huhsp.org.br.
Rosana Fiorini PucciniUniversidade Federal de São Paulo, Departamento de Pediatria, São Paulo, SP, Brazil.
Antónia MachadoUniversidade Federal de São Paulo, Departamento de Medicina, São Paulo, SP, Brazil.
Maria Gisele GonçalvesInstituto Adolfo Lutz, Instituto de Imunologia, São Paulo, SP, Brazil.
Suely TuboiGSK Brazil, Rio de Janeiro, RJ, Brazil.
Eliana de BarrosGSK Brazil, Rio de Janeiro, RJ, Brazil.
Raghavendra DevadigaGSK, Bangalore, India.
Eduardo Ortega-BarriaGSK, Ciudad de Panama, Panama.
Romulo ColindresGSK Brazil, Rio de Janeiro, RJ, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meningococcal carriage is a prerequisite for invasive infection. This cross-sectional study assessed the pharyngeal carriage prevalence in healthy subjects aged 1-24 years in Embu das Artes city, São Paulo, Brazil. Pharyngeal swabs were examined for the presence of Neisseria meningitidis. The isolates were tested for different serogroups using agglutination and polymerase chain reaction. A logistic regression model assessed any independent association between Neisseria meningitidis carriage and various risk factors. A total of 87/967 subjects (9%, 95% Confidence Interval (CI): 7.3-11.0) tested positive for N. meningitidis: 6.2% (95% CI: 3.8-9.4) in 1-4 years, 8.5% (95% CI: 5.1-13.0) in 5-9 years, 12.5% (95% CI: 7.8-18.6) in 10-14 years, 12.6% (95% CI: 7.4-19.7) in 15-19 years and 9% (95% CI: 4.9-14.9) in 20-24 years age groups. Highest carriage prevalence was observed in adolescents 10-19 years old. Serogroup C was predominant (18.4%) followed by serogroup B (12.6%). The 15-19 years age group showed a significant association between number of household members and carriers of N. meningitidis. This cross-sectional study is the first in Brazil to evaluate meningococcal carriage prevalence and associated factors in a wide age range.

Indexed as

AdolescentAge DistributionBrazilCarrier StateChildChild, PreschoolCross-Sectional StudiesFemaleHumansInfantMaleMeningococcal InfectionsNeisseria meningitidisPharynxPrevalenceRisk FactorsCarriageMeningococcal diseaseNeisseria meningitidisPharyngealSerogroup

Identifiers

PMID28711456
PMCPMC9425485

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.