Evidence map›Paper›PMID 28711142›Full record

ReviewRheumatic diseases clinics of North America2017

Genetics and the Causes of Ankylosing Spondylitis.

Aimee Hanson, Matthew A Brown

Open access · greenAbstract readReview
In one paragraph

Review in Rheumatic diseases clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 129 citations in OpenAlex.

  1. Article
  2. Article
  3. [Role of HLA genetic variants in autoimmune diseases].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Review
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  18. Association between HLA-B*27:04 and genetic susceptibility to ankylosing spondylitis in Hunan Province.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Aimee HansonTranslational Research Institute, Princess Alexandra Hospital, University of Queensland Diamantina Institute, Woolloongabba, Brisbane, Queensland, Australia.
Matthew A BrownInstitute of Health and Biomedical Innovation, Translational Research Institute, Princess Alexandra Hospital, Queensland University of Technology, Woolloongabba, Brisbane, Queensland, Australia. Electronic address: matt.brown@qut.edu.au.
Translational Research Institute · AU

Funding

The Genetic Basis of AS SusceptibilityP01AR052915 · NIAMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BROWN, MATTHEW A · 2006 to 2016
$10.9M
NIAMS NIH HHS P01 AR052915
6 · The paper itself

Abstract

Ankylosing spondylitis (AS) is a common inflammatory arthritis in which genetic factors are the primary determinants of disease risk and severity. Substantial progress has been made in identifying genetic pathways involved in the disease, and in translating those discoveries to drug discovery programs. Recently discovered novel disease pathways include those involved in control of DNA methylation, bacterial sensing, and mucosal immunity. Additional pathways are likely to be identified as a higher proportion of the genetic risk of AS is determined.

Indexed as

Genetic PleiotropyGenetic Predisposition to DiseaseHLA-B27 AntigenHumansSpondylitis, AnkylosingHLA-B27 AntigenAnkylosing spondylitisAssociationAxial spondyloarthritisGeneticsHeritabilitySNP

Identifiers

PMID28711142
PMCPMC6982368
OpenAlexW2734764199

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.