ArticleJournal of biomedical science2017
PA-6 inhibits inward rectifier currents carried by V93I and D172N gain-of-function K
Article in Journal of biomedical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- The network of cardiac KNaunyn-Schmiedeberg's archives of pharmacology · 2024Review
- Kir2.1-mediated membrane potential promotes nutrient acquisition and inflammation through regulation of nutrient transporters.Nature communications · 2022Article
- Alzheimer's disease and cerebrovascular pathology alter inward rectifier potassium (KBritish journal of pharmacology · 2022Article
- Quantitative Analysis of the Cytoskeleton's Role in Inward Rectifier KFrontiers in physiology · 2021Article
- Electrophysiological and Pharmacological Characterization of Human Inwardly Rectifying KAssay and drug development technologies · 2019Article
- Identification of a PEST Sequence in Vertebrate KFrontiers in physiology · 2019Article
- Genetics of atrial fibrillation: an update.Current opinion in cardiology · 2018Review
- Molecular Insights into the Short QT Syndrome.The Journal of innovations in cardiac rhythm management · 2018Article
- Cardiac Arrhythmias and Antiarrhythmic Drugs: An Autophagic Perspective.Frontiers in physiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundThe inward rectifier potassium current I
methodsMolecular modelling was performed with the human K
resultsPA-6 docking in the V93I/D172N double mutant homology model of K
conclusions1) KCNJ2 gain-of-function mutations V93I and D172N in the K
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.