ArticleInternational journal of cancer2017
Dietary fiber intake and head and neck cancer risk: A pooled analysis in the International Head and Neck Cancer Epidemiology consortium.
Article in International journal of cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Meta-analysis of the association between dietary inflammatory index (DII) and upper aerodigestive tract cancer risk.Medicine · 2020Pooled it
- Quantitative assessment of the relationship between Fas/FasL genes polymorphisms and head and neck cancer risk.Medicine · 2018Pooled it
- Adherence to a low-fat dietary pattern reduces head and neck cancer risk: evidence from the PLCO trial.Nutrition journal · 2024Trial
- Associations of combined lifestyle and genetic risk with incident head and neck cancer: a prospective study in the UK Biobank.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Nutritional Determinants of Oral Cancer: A Global Population Attributable Fraction Analysis Across 185 Countries (1990-2018).International dental journal · 2026Article
- Association Between the Dietary Inflammatory Index (DII) and Head and Neck Cancer Incidence-A Narrative Review.Nutrients · 2026Review
- Intake of prebiotic fibers and the risk of laryngeal cancer: the PrebiotiCa study.European journal of nutrition · 2023Article
- Adherence to the Dietary Approaches to Stop Hypertension (DASH) Eating Pattern Reduces the Risk of Head and Neck Cancer in American Adults Aged 55 Years and Above: A Prospective Cohort Study.The journal of nutrition, health & aging · 2023Article
- Identification of p53-target genes in human papillomavirus-associated head and neck cancer by integrative bioinformatics analysis.Frontiers in oncology · 2023Article
- Plasma miR-151-3p as a Candidate Diagnostic Biomarker for Head and Neck Cancer: A Cross-sectional Study within the INHANCE Consortium.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022Article
- Article
- Dietary patterns with combined and site-specific cancer incidence in Alberta's Tomorrow Project cohort.European journal of clinical nutrition · 2022Article
- Trends in the incidence of head and neck cancer by subsite between 1993 and 2015 in Japan.Cancer medicine · 2022Article
- Relationship Between Dietary Fiber and Vitamin C Intake and Oral Cancer.Frontiers in public health · 2022Article
- Head and neck cancer risk factors in the French West Indies.BMC cancer · 2021Article
- Dietary fiber intake from fresh and preserved food and risk of nasopharyngeal carcinoma: observational evidence from a Chinese population.Nutrition journal · 2021Observational
- Lessons learned from the INHANCE consortium: An overview of recent results on head and neck cancer.Oral diseases · 2021Review
- Incidence and mortality of oral and oropharyngeal cancer in China, 2015.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2020Article
- Article
- Dietary Fiber, Whole Grains, and Head and Neck Cancer Prognosis: Findings from a Prospective Cohort Study.Nutrients · 2019Article
Corrections and comments
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Authors and funding
26 authors at 19 institutions in 7 countries.
Funding
Abstract
The possible role of dietary fiber in the etiology of head neck cancers (HNCs) is unclear. We used individual-level pooled data from ten case-control studies (5959 cases and 12,248 controls) participating in the International Head and Neck Cancer Epidemiology (INHANCE) consortium, to examine the association between fiber intake and cancer of the oral cavity/pharynx and larynx. Odds Ratios (ORs) and their 95% Confidence Intervals (CIs) were estimated using unconditional multiple logistic regression applied to quintile categories of non-alcohol energy-adjusted fiber intake and adjusted for tobacco and alcohol use and other known or putative confounders. Fiber intake was inversely associated with oral and pharyngeal cancer combined (OR for 5th vs. 1st quintile category = 0.49, 95% CI: 0.40-0.59; p for trend <0.001) and with laryngeal cancer (OR = 0.66, 95% CI: 0.54-0.82, p for trend <0.001). There was, however, appreciable heterogeneity of the estimated effect across studies for oral and pharyngeal cancer combined. Nonetheless, inverse associations were consistently observed for the subsites of oral and pharyngeal cancers and within most strata of the considered covariates, for both cancer sites. Our findings from a multicenter large-scale pooled analysis suggest that, although in the presence of between-study heterogeneity, a greater intake of fiber may lower HNC risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.