Evidence map›Paper›PMID 28710602›Full record

ArticleIn vitro cellular & developmental biology. Animal2017

Eldecalcitol (ED-71), an analog of 1α,25(OH)

T Shintani, F Takatsu, S N Z Rosli, E Usui, A Hamada, K Sumi, Y Hayashido, S Toratani, Tetsuji Okamoto

Abstract read
PubMed Publisher
In one paragraph

Article in In vitro cellular & developmental biology. Animal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Inhibition of vitamin D analog eldecalcitol on hepatomaOpen medicine (Warsaw, Poland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

T ShintaniCenter of Oral Clinical Examination, Hiroshima University Hospital, Hiroshima, Japan.
F TakatsuOral Maxillofacial Surgery, Hiroshima University Hospital, Hiroshima, Japan.
S N Z RosliDepartment of Molecular Oral Medicine and Maxillofacial Surgery, Division of Applied Life Sciences, Graduate Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, 734-8553, Japan.
E UsuiOral Maxillofacial Surgery, Hiroshima University Hospital, Hiroshima, Japan.
A HamadaOral Maxillofacial Surgery, Hiroshima University Hospital, Hiroshima, Japan.
K SumiDepartment of Molecular Oral Medicine and Maxillofacial Surgery, Division of Applied Life Sciences, Graduate Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, 734-8553, Japan.
Y HayashidoOral Maxillofacial Surgery, Hiroshima University Hospital, Hiroshima, Japan.
S TorataniDepartment of Molecular Oral Medicine and Maxillofacial Surgery, Division of Applied Life Sciences, Graduate Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, 734-8553, Japan.
Tetsuji OkamotoDepartment of Molecular Oral Medicine and Maxillofacial Surgery, Division of Applied Life Sciences, Graduate Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, 734-8553, Japan. tetsuok@hiroshima-u.ac.jp.
Hiroshima University Hospital · JPHiroshima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heparin-binding protein 17 (HBp17)/fibroblast growth factor-binding protein-1 (FGFBP-1) was first purified from medium conditioned by A431 cells for its capacity to bind to fibroblast growth factors 1 and 2 (FGF-1 and -2). Among FGF family members, FGF-2 is a potent mitogen for various cell types, including vascular endothelial cells, fibroblasts, and cancer cells such as oral squamous cell carcinoma (OSCC) cells. Besides being well known in bone metabolism, the active form of vitamin D

Indexed as

AnimalsApoptosisCalcitriolCarcinoma, Squamous CellCarrier ProteinsCell Line, TumorCell ProliferationDown-RegulationFibroblast Growth Factor 2Intercellular Signaling Peptides and ProteinsMice, NudeMouth NeoplasmsNeovascularization, PathologicNF-KappaB Inhibitor alphaPromoter Regions, GeneticReceptors, CalcitriolCalcitriolCarrier ProteinseldecalcitolFGFBP1 protein, humanFibroblast Growth Factor 2Intercellular Signaling Peptides and ProteinsNF-KappaB Inhibitor alphaReceptors, CalcitriolRNA, Small InterferingVitamin D1,25(OH)2D3AngiogenesisEldecalcitol (ED-71)FGF-2HBp17/FGFBP-1Oral squamous cell carcinoma

Identifiers

PMID28710602
OpenAlexW2734830334

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.