Evidence map›Paper›PMID 28710577›Full record

ArticleEuropean radiology2018

Detection of small-bowel tumours with CT enteroclysis using carbon dioxide and virtual enteroscopy: A preliminary study.

Anthony Dohan, Mourad Boudiaf, Xavier Dray, Elia Samaha, Christophe Cellier, Marine Camus, Clarisse Eveno, Raphael Dautry, Philippe Soyer

Abstract read
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In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Anthony DohanDepartment of Body and Interventional Imaging, Hôpital Lariboisière - Assistance Publique-Hôpitaux de Paris, 2 Rue Ambroise Paré, 75010, Paris, France. anthony.dohan@aphp.fr.ORCID http://orcid.org/0000-0002-8732-5603
Mourad BoudiafDepartment of Body and Interventional Imaging, Hôpital Lariboisière - Assistance Publique-Hôpitaux de Paris, 2 Rue Ambroise Paré, 75010, Paris, France.
Xavier DrayDepartment of Digestive Diseases, Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris, 184 Rue du Faubourg Saint-Antoine, 75012, Paris, France.
Elia SamahaGastroenterology and Endoscopy Unit, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, 20 Rue Leblanc, 75015, Paris, France.
Christophe CellierGastroenterology and Endoscopy Unit, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, 20 Rue Leblanc, 75015, Paris, France.
Marine CamusUniversité Sorbonne Paris Cité, Paris Descartes, Paris, France.
Clarisse EvenoUniversité Sorbonne Paris Cité, Paris Diderot, INSERM UMR 965, 2 Rue Ambroise Paré, 75010, Paris, France.
Raphael DautryDepartment of Body and Interventional Imaging, Hôpital Lariboisière - Assistance Publique-Hôpitaux de Paris, 2 Rue Ambroise Paré, 75010, Paris, France.
Philippe SoyerUniversité Sorbonne Paris Cité, Paris Diderot, INSERM UMR 965, 2 Rue Ambroise Paré, 75010, Paris, France.
Assistance Publique – Hôpitaux de Paris · FRInserm · FRDélégation Paris 5 · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this prospective study was to evaluate the feasibility, tolerance and performance of virtual enteroscopy (VE) using carbon dioxide for small-bowel distension in patients with suspected small-bowel tumours (SBTs). PATIENTS AND

methodsAfter IRB approval, 17 patients with suspected SBTs were prospectively included. Radiation dose was compared to 34 matched patients (2 for 1) for age, gender and body weight, who had undergone CT-enteroclysis with neutral contrast (CTE). Performance of VE was evaluated through comparison with the current standard of reference, including surgery and/or enteroscopy and/or follow-up.

resultsTolerance was excellent in 16/17 patients (94%). The radiation dose was lower for VE than for CTE (533 ± 282 vs. 974 ± 505 mGy.cm; p = 0.002). With VE, a total of 25 polyps >5 mm in size were depicted in 12/17 patients. On a per-lesion analysis, sensitivity and positive predictive value of VE were 92.0% and 92.0%, respectively. On a per-segment analysis VE had a sensitivity and specificity of 95.0% and 87.0%, respectively.

conclusionOur preliminary study suggests that VE is a feasible and well-tolerated technique with high sensitivity and specificity for the diagnosis of SBT. KEY POINTS: • Virtual enteroscopy is feasible and well tolerated. • Virtual enteroscopy appears to be accurate for detection of small-bowel tumours. • Sensitivity and PPV of virtual enteroscopy is 92.0% and 92.0%. • Radiation dose is lower with virtual enteroscopy compared to MDCT-enteroclysis.

Indexed as

AdolescentAdultCarbon DioxideEndoscopy, GastrointestinalFemaleHumansInsufflationIntestinal NeoplasmsIntestine, SmallMaleMiddle AgedProspective StudiesReproducibility of ResultsSensitivity and SpecificityTomography, X-Ray ComputedYoung AdultCarbon DioxideCT-enteroclysisLesion detectionObscure gastrointestinal bleedingSmall bowel tumoursVirtual enteroscopy

Identifiers

PMID28710577
OpenAlexW2735190831

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.