Evidence map›Paper›PMID 28710541›Full record

ArticlePurinergic signalling2017

Injury-induced purinergic signalling molecules upregulate pluripotency gene expression and mitotic activity of progenitor cells in the zebrafish retina.

Matías P Medrano, Claudio A Bejarano, Ariadna G Battista, Graciela D Venera, Ramón O Bernabeu, Maria Paula Faillace

Open access · bronzeAbstract read
In one paragraph

Article in Purinergic signalling, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Müller Glia-Mediated Retinal Regeneration.Molecular neurobiology · 2021
    Review
  4. Review
  5. Reprogramming Müller Glia to Regenerate Retinal Neurons.Annual review of vision science · 2020
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Matías P MedranoInstituto de Fisiología y Biofísica Prof. Bernardo Houssay (IFIBIO-Houssay), UBA y Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Claudio A BejaranoInstituto de Fisiología y Biofísica Prof. Bernardo Houssay (IFIBIO-Houssay), UBA y Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Ariadna G BattistaInstituto de Química y Fisicoquímica Biológicas (IQUIFIB) Prof. Alejandro Paladini, UBA-CONICET, Buenos Aires, Argentina.
Graciela D VeneraInstituto Universitario Italiano de Rosario (IUNIR), Santa Fe, Argentina.
Ramón O BernabeuInstituto de Fisiología y Biofísica Prof. Bernardo Houssay (IFIBIO-Houssay), UBA y Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.
Maria Paula FaillaceInstituto de Fisiología y Biofísica Prof. Bernardo Houssay (IFIBIO-Houssay), UBA y Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina. pfaillace@qb.ffyb.uba.ar.ORCID http://orcid.org/0000-0002-9230-8138
Consejo Nacional de Investigaciones Científicas y Técnicas · ARInstituto Universitario Italiano de Rosario · ARUniversidad de Flores · AR

Funding

Consejo Nacional de Investigaciones Científicas y Técnicas PIP 0079COUniversidad de Buenos Aires (UBA), Argentina UBACYT 0061Universidad de Buenos Aires (UBA), Argentina UBACYT 0823
6 · The paper itself

Abstract

Damage in fish activates retina repair that restores sight. The purinergic signalling system serves multiple homeostatic functions and has been implicated in cell cycle control of progenitor cells in the developing retina. We examined whether changes in the expression of purinergic molecules were instrumental in the proliferative phase after injury of adult zebrafish retinas with ouabain. P2RY

Indexed as

AnimalsGene Expression RegulationMitosisNerve RegenerationNeural Stem CellsNeurogenesisPluripotent Stem CellsReceptors, Purinergic P2Y1RetinaSignal TransductionUp-RegulationZebrafishReceptors, Purinergic P2Y1E-NTPDasesExtracellular nucleotidesPluripotency genesProgenitor cellPurinergic receptorsRetina regeneration

Identifiers

PMID28710541
PMCPMC5714835
OpenAlexW2734794092

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.