Evidence map›Paper›PMID 28710339›Full record

Trial reportThorax2017

Impact of low-dose CT screening on smoking cessation among high-risk participants in the UK Lung Cancer Screening Trial.

Kate Brain, Ben Carter, Kate J Lifford, Olivia Burke, Anand Devaraj, David R Baldwin, Stephen Duffy, John K Field

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Thorax, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03394703 (Korean Lung Cancer Screening Project for High-risk Smokers to Evaluate Effectiveness and Feasibility of Lung Cancer Screening With Low-dose Computed Tomography for Implementing National Cancer Screening Program), which is not on this map. Cited by 73 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03394703 unknown statusnot on this map

Korean Lung Cancer Screening Project for High-risk Smokers to Evaluate Effectiveness and Feasibility of Lung Cancer Screening With Low-dose Computed Tomography for Implementing National Cancer Screening Program

TypeobservationalSponsorNational Cancer Center, KoreaRan2017 to 2018Enrolled8,000ConditionsLung Cancer
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
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  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
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  14. Article
  15. Review
  16. Article
  17. Impact of Low-Dose Computed Tomography Findings on Cigarette Smoking Cessation Among High-Risk Adults Participating in Lung Cancer Screening.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Observational
  18. Review
  19. "Because That is the Right Thing to do": A Focus Group Study of Australian Expert Perspectives on Offering Smoking Cessation Support in Lung Cancer Screening.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Article
  20. Observational

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Kate BrainDivision of Population Medicine, Cardiff University School of Medicine, Cardiff, UK.
Ben CarterDivision of Population Medicine, Cardiff University School of Medicine, Cardiff, UK.
Kate J LiffordDivision of Population Medicine, Cardiff University School of Medicine, Cardiff, UK.
Olivia BurkeDivision of Population Medicine, Cardiff University School of Medicine, Cardiff, UK.
Anand DevarajRoyal Brompton and Harefield NHS Trust, London, UK.
David R BaldwinDepartment of Respiratory Medicine, Nottingham University Hospitals, Nottingham, UK.ORCID 0000-0001-8410-7160
Stephen DuffyQueen Mary University of London, London, UK.
John K FieldRoy Castle Lung Cancer Research Programme, Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, UK.

Funding

Department of Health 09/61/01Department of Health 09/61/501
6 · The paper itself

Abstract

backgroundSmoking cessation was examined among high-risk participants in the UK Lung Cancer Screening (UKLS) Pilot Trial of low-dose CT screening.

methodsHigh-risk individuals aged 50-75 years who completed baseline questionnaires were randomised to CT screening (intervention) or usual care (no screening control). Smoking habit was determined at baseline using self-report. Smokers were asked whether they had quit smoking since joining UKLS at T

resultsOf a total 4055 individuals randomised to CT screening or control, 1546 were baseline smokers (759 intervention, 787 control). Smoking cessation rates were 8% (control n=36/479) versus 14% (intervention n=75/527) at T

conclusionsCT lung cancer screening for high-risk participants presents a teachable moment for smoking cessation, especially among those who receive a positive scan result. Further behavioural research is needed to evaluate optimal strategies for integrating smoking cessation intervention with stratified lung cancer screening. TRIAL REGISTRATION NUMBER: Results, ISRCTN 78513845.

Indexed as

Smoking CessationAgedEarly Detection of CancerEnglandFemaleHumansLung NeoplasmsMaleMass ScreeningMiddle AgedPilot ProjectsRadiation DosageSurveys and QuestionnairesTomography, X-Ray ComputedLung CancerSmoking cessation

Identifiers

PMID28710339
PMCPMC5738533

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.