Evidence map›Paper›PMID 28710288›Full record

ReviewBiochemical Society transactions2017

Post-transcriptional control of gene expression following stress: the role of RNA-binding proteins.

Robert Harvey, Veronica Dezi, Mariavittoria Pizzinga, Anne E Willis

Open access · hybridAbstract readComparative StudyReview
In one paragraph

Review in Biochemical Society transactions, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Review
  3. Genome-Wide Analysis of YTH Domain Proteins inPlants (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. OOPSIE (OOPS informatics extension).Bioinformatics advances · 2026
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Robert HarveyMedical Research Council Toxicology Unit, Lancaster Rd, Leicester LE1 9HN, U.K.
Veronica DeziMedical Research Council Toxicology Unit, Lancaster Rd, Leicester LE1 9HN, U.K.
Mariavittoria PizzingaMedical Research Council Toxicology Unit, Lancaster Rd, Leicester LE1 9HN, U.K. mp540@le.ac.uk aew5@le.ac.uk.
Anne E WillisMedical Research Council Toxicology Unit, Lancaster Rd, Leicester LE1 9HN, U.K. mp540@le.ac.uk aew5@le.ac.uk.
Medical Research Council · GB

Funding

10071/Z/15/Z WELCOME TRUST5TR00 MRCMedical Research Council MC_UP_A600_1023
6 · The paper itself

Abstract

The ability of mammalian cells to modulate global protein synthesis in response to cellular stress is essential for cell survival. While control of protein synthesis is mediated by the regulation of eukaryotic initiation and elongation factors, RNA-binding proteins (RBPs) provide a crucial additional layer to post-transcriptional regulation. RBPs bind specific RNA through conserved RNA-binding domains and ensure that the information contained within the genome and transcribed in the form of RNA is exported to the cytoplasm, chemically modified, and translated prior to folding into a functional protein. Thus, this group of proteins, through mediating translational reprogramming, spatial reorganisation, and chemical modification of RNA molecules, have a major influence on the robust cellular response to external stress and toxic injury.

Indexed as

Gene Expression RegulationModels, BiologicalStress, PhysiologicalAnimalsCold-Shock ResponseDNA DamageEndoplasmic Reticulum StressHeat-Shock ResponseHumansMethylationOxidative StressProtein Interaction Domains and MotifsRNA-Binding ProteinsRNA, MessengerRNA Processing, Post-TranscriptionalRNA-Binding ProteinsRNA, MessengerepitranscriptomeRNA-binding proteinsstress granulesstress responsetranslationtranslational reprogramming

Identifiers

PMID28710288
PMCPMC5655797
OpenAlexW2736059730

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.