Evidence map›Paper›PMID 28710266›Full record

ArticleApplied and environmental microbiology2017

Specificity of Subtilin-Mediated Activation of Histidine Kinase SpaK.

Christoph Geiger, Tobias Spieß, Sophie Marianne Korn, Peter Kötter, Karl-Dieter Entian

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christoph GeigerInstitute for Molecular Biosciences, Goethe University, Frankfurt, Germany.
Tobias SpießInstitute for Molecular Biosciences, Goethe University, Frankfurt, Germany.
Sophie Marianne KornInstitute for Molecular Biosciences, Goethe University, Frankfurt, Germany.
Peter KötterInstitute for Molecular Biosciences, Goethe University, Frankfurt, Germany koetter@bio.uni-frankfurt.de entian@bio.uni-frankfurt.de.
Karl-Dieter EntianInstitute for Molecular Biosciences, Goethe University, Frankfurt, Germany koetter@bio.uni-frankfurt.de entian@bio.uni-frankfurt.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoinduction via two-component systems is a widespread regulatory mechanism that senses environmental and metabolic changes. Although the lantibiotics nisin and subtilin are closely related and share the same lanthionine ring structure, they autoinduce their biosynthesis in a highly specific manner. Subtilin activates only the two-component system SpaRK of

Indexed as

autoinductionBacillus subtilishistidine kinaselantibioticsnisinpeptide antibioticsquorum quenchingsensor domainsubtilintwo-component regulatory systems

Identifiers

PMID28710266
PMCPMC5583494

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.