SynthesisAdvances in nutrition (Bethesda, Md.)2017
Energy, Protein, Carbohydrate, and Lipid Intakes and Their Effects on Morbidity and Mortality in Critically Ill Adult Patients: A Systematic Review.
Synthesis in Advances in nutrition (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review of the management of perioperative tube-fed enteral nutrition in esophageal cancer patients.Frontiers in nutrition · 2026Pooled it
- Article
- Evaluating a Clinical Decision Support System for Optimizing Total Parenteral Nutrition in Adult Oncology Patients.Nutrients · 2026Article
- International society of sports nutrition position stand: nutrition and weight cut strategies for mixed martial arts and other combat sports.Journal of the International Society of Sports Nutrition · 2025Review
- The role of bedside ultrasound in nutritional monitoring: an observational study on the correlation between quadriceps muscle layer thickness and prealbumin in ICU patients.BMC anesthesiology · 2025Observational
- Effect of postoperative enteral protein supplementation on nitrogen balance in critically ill children.Clinical and experimental pediatrics · 2025Article
- The role of adipose tissue in critical illness-induced skeletal muscle wasting-new considerations for treatment approaches.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Review
- Nutritional practices and impact of feeding adequacy on clinical outcomes in Chinese respiratory intensive care units patients: a prospective observational study (ORIENT study).Frontiers in nutrition · 2025Article
- The influence of high-fat diet and energy-restricted diet on hematopoietic stem cells: mechanisms and implications.Frontiers in immunology · 2025Review
- Alpha-melanocyte-stimulating hormone contributes to an anti-inflammatory response to lipopolysaccharide.Molecular metabolism · 2024Article
- Yantiao Formula Intervention in Rats with Sepsis: Network Pharmacology and Experimental Analysis.Combinatorial chemistry & high throughput screening · 2024Article
- Article
- Multiple portions enteral nutrition and chyme reinfusion of a blunt bowel injury patient with hyperbilirubinemia undergoing open abdomen: A case report.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2023Article
- Article
- Dietary Modifications in Critically-Ill Patients: A Comparison of Persian Medicine and Conventional Medicine Perspectives.Evidence-based complementary and alternative medicine : eCAM · 2023Review
- Article
- Factors associated with the need of parenteral nutrition in critically ill patients after the initiation of enteral nutrition therapy.Frontiers in nutrition · 2023Article
- Article
- Lipid-Free Parenteral Nutrition Is Associated with an Increased Risk of Hepatic Dysfunction in Surgical Critically Ill Patients: A Retrospective Observational Study.Healthcare (Basel, Switzerland) · 2021Article
- Interaction of Severe Acute Respiratory Syndrome Coronavirus 2 and Diabetes.Frontiers in endocrinology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The guidelines for nutritional support in critically ill adult patients differ in various aspects. The optimal amount of energy and nutritional substrates supplied is important for reducing morbidity and mortality, but unfortunately this is not well known, because the topic is complex and every patient is individual. The aim of this review was to gather recent pertinent information concerning the nutritional support of critically ill patients in the intensive care unit (ICU) with respect to the energy, protein, carbohydrate, and lipid intakes and the effect of their specific utilization on morbidity and mortality. Enteral nutrition (EN) is generally recommended over parenteral nutrition (PN) and is beneficial when administered within 24-48 h after ICU admission. In contrast, early PN does not provide substantial advantages in terms of morbidity and mortality, and the time when it is safe and beneficial remains unclear. The most advantageous recommendation seems to be administration of a hypocaloric (<20 kcal · kg
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Registered trials
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