Evidence map›Paper›PMID 28710073›Full record

ArticleJournal of lipid research2017

Zinc mediates the SREBP-SCD axis to regulate lipid metabolism in

Jing-Jing Zhang, Jun-Jun Hao, Yu-Ru Zhang, Yan-Li Wang, Ming-Yi Li, Hui-Lai Miao, Xiao-Ju Zou, Bin Liang

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Jing-Jing ZhangKey Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China; Department of Hepatobiliary Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China.
Jun-Jun HaoState Key Laboratory of Genetic Resources and Evolutionary and Functional Genomics, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
Yu-Ru ZhangCollege of Fisheries, Henan Normal University, Xinxiang, Henan 453007, China.
Yan-Li WangKey Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.
Ming-Yi LiDepartment of Hepatobiliary Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China.
Hui-Lai MiaoDepartment of Hepatobiliary Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China.
Xiao-Ju ZouDepartment of Life Science and Biotechnology, Key Laboratory of Special Biological Resource Development and Utilization of University in Yunnan Province, Kunming University, Kunming 650214, China. Electronic address: xiaojuzou@163.com.
Bin LiangKey Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China; Department of Hepatobiliary Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China. Electronic address: liangb@mail.kiz.ac.cn.
Kunming Institute of Zoology · CNGuangdong Medical College · CNChinese Academy of Sciences · CNHenan Normal University · CNKunming University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maintenance of lipid homeostasis is crucial for cells in response to lipid requirements or surplus. The SREBP transcription factors play essential roles in regulating lipid metabolism and are associated with many metabolic diseases. However, SREBP regulation of lipid metabolism is still not completely understood. Here, we showed that reduction of SBP-1, the only homolog of SREBPs in

Indexed as

Lipid MetabolismAdipose TissueAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsGenomicsMutationStearoyl-CoA DesaturaseSterol Regulatory Element Binding Protein 1Transcription FactorsZincCaenorhabditis elegans ProteinsSBP-1 protein, C elegansStearoyl-CoA DesaturaseSterol Regulatory Element Binding Protein 1SUR-7 protein, C elegansTranscription FactorsZinclipid homeostasisstearoyl-CoA desaturasesterol regulatory element-binding protein

Identifiers

PMID28710073
PMCPMC5580898
OpenAlexW2735720940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.