Evidence map›Paper›PMID 28710067›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2017

A comparison of passive hindlimb cycling and active upper-limb exercise provides new insights into systolic dysfunction after spinal cord injury.

Kathryn M DeVeau, Kathryn A Harman, Jordan W Squair, Andrei V Krassioukov, David S K Magnuson, Christopher R West

Registry-linked trialOpen access · greenAbstract readComparative Study
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04358679 (Effects of Upper Limb Ergometer on Pulmonary Function Among Patients With Spinal Cord Injury.), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04358679 nacompletednot on this mapstarted 2019, after this paper: background citation

Effects of Upper Limb Ergometer on Pulmonary Function Among Patients With Spinal Cord Injury.

TypeinterventionalSponsorRiphah International UniversityRan2019 to 2020Enrolled44ConditionsSpinal Cord InjuriesArmsConventional Treatment, Upper Limb ergometer training
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Kathryn M DeVeauInternational Collaboration on Repair Discoveries, Vancouver, British Columbia, Canada.
Kathryn A HarmanInternational Collaboration on Repair Discoveries, Vancouver, British Columbia, Canada.
Jordan W SquairInternational Collaboration on Repair Discoveries, Vancouver, British Columbia, Canada.
Andrei V KrassioukovDivision of Physical Medicine and Rehabilitation, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
David S K MagnusonKentucky Spinal Cord Injury Research Institute, University of Louisville, Louisville, Kentucky.
Christopher R WestInternational Collaboration on Repair Discoveries, Vancouver, British Columbia, Canada; west@icord.org.
University of British Columbia · CAUniversity of Louisville · USGF Strong Rehabilitation Centre · CAInternational Collaboration On Repair Discoveries · CA

Funding

Signaling pathways in neuronal susceptibility to hypoxiaP20RR015576 · NCRR · UNIVERSITY OF LOUISVILLE · PI GOZAL, EVELYNE · 2000 to 2009
$18.5M
Re-training locomotor circuitry in a rat model of spinal cord injuryR56NS052292 · NINDS · UNIVERSITY OF LOUISVILLE · PI MAGNUSON, DAVID SK · 2011 to 2011
$373k
NCRR NIH HHS P20 RR015576NINDS NIH HHS R56 NS052292
6 · The paper itself

Abstract

Active upper-limb and passive lower-limb exercise are two interventions used in the spinal cord injury (SCI) population. Although the global cardiac responses have been previously studied, it is unclear how either exercise influences contractile cardiac function. Here, the cardiac contractile and volumetric responses to upper-limb (swim) and passive lower-limb exercise were investigated in rodents with a severe high-thoracic SCI. Animals were divided into control (CON), SCI no exercise (NO-EX), SCI passive hindlimb cycling (PHLC), or SCI swim (SWIM) groups. Severe contusion SCI was administered at the T2 level. PHLC and SWIM interventions began on

Indexed as

BicyclingPhysical Conditioning, AnimalPhysical Conditioning, HumanAnimalsBlood PressureEchocardiography, StressHindlimbHumansMaleMyocardial ContractionRatsRats, WistarRegional Blood FlowSpinal Cord InjuriesSwimmingUpper Extremitycardiac functionexercisepressure-volumespinal cord injury

Identifiers

PMID28710067
PMCPMC9925118
OpenAlexW2735811052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.