Evidence map›Paper›PMID 28709453›Full record

ArticleBMC medical informatics and decision making2017

Validation of multisource electronic health record data: an application to blood transfusion data.

Loan R van Hoeven, Martine C de Bruijne, Peter F Kemper, Maria M W Koopman, Jan M M Rondeel, Anja Leyte, Hendrik Koffijberg, Mart P Janssen, Kit C B Roes

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Digital Health Data Quality Issues: Systematic Review.Journal of medical Internet research · 2023
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Loan R van HoevenJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Universiteitsweg 100, 3508, GA, Utrecht, The Netherlands. l.r.vanhoeven-3@umcutrecht.nl.
Martine C de BruijneDepartment of Public and Occupational Health, EMGO Institute, VU University Medical Center, Van der Boechorststraat 7, 1081, BT, Amsterdam, The Netherlands.
Peter F KemperTransfusion Technology Assessment Department, Sanquin Research, Plesmanlaan 125, 1066, CX, Amsterdam, The Netherlands.
Maria M W KoopmanDepartment of Transfusion Medicine, Sanquin Blood bank, Plesmanlaan 125, 1066, CX, Amsterdam, The Netherlands.
Jan M M RondeelIsala, Dr. Van Heesweg 2, 8025, AB, Zwolle, The Netherlands.
Anja LeyteOLVG, Oosterpark 9, 1091, AC, Amsterdam, The Netherlands.
Hendrik KoffijbergDepartment of Health Technology & Services Research, MIRA Institute for biomedical technology and technical medicine, University of Twente, Drienerlolaan 5, 7522, NB, Enschede, The Netherlands.
Mart P JanssenJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Universiteitsweg 100, 3508, GA, Utrecht, The Netherlands.
Kit C B RoesJulius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Universiteitsweg 100, 3508, GA, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough data from electronic health records (EHR) are often used for research purposes, systematic validation of these data prior to their use is not standard practice. Existing validation frameworks discuss validity concepts without translating these into practical implementation steps or addressing the potential influence of linking multiple sources. Therefore we developed a practical approach for validating routinely collected data from multiple sources and to apply it to a blood transfusion data warehouse to evaluate the usability in practice.

methodsThe approach consists of identifying existing validation frameworks for EHR data or linked data, selecting validity concepts from these frameworks and establishing quantifiable validity outcomes for each concept. The approach distinguishes external validation concepts (e.g. concordance with external reports, previous literature and expert feedback) and internal consistency concepts which use expected associations within the dataset itself (e.g. completeness, uniformity and plausibility). In an example case, the selected concepts were applied to a transfusion dataset and specified in more detail.

resultsApplication of the approach to a transfusion dataset resulted in a structured overview of data validity aspects. This allowed improvement of these aspects through further processing of the data and in some cases adjustment of the data extraction. For example, the proportion of transfused products that could not be linked to the corresponding issued products initially was 2.2% but could be improved by adjusting data extraction criteria to 0.17%.

conclusionsThis stepwise approach for validating linked multisource data provides a basis for evaluating data quality and enhancing interpretation. When the process of data validation is adopted more broadly, this contributes to increased transparency and greater reliability of research based on routinely collected electronic health records.

Indexed as

Blood TransfusionElectronic Health RecordsHospitalsMedical Record LinkageValidation Studies as TopicHumansNetherlandsData qualityData validationLinkage of multiple sourcesRoutinely collected data

Identifiers

PMID28709453
PMCPMC5512751

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.