ArticleBMC oral health2017
Genotypic diversity and phenotypic traits of Streptococcus mutans isolates and their relation to severity of early childhood caries.
Article in BMC oral health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- [Age-Related Changes in the Oral Microbiota].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026Review
- Strain-level genomic variation ofPeerJ · 2026Article
- Multilocus sequence typing and phenotypic properties of Streptococcus mutans from Thai children with different caries statuses.BMC oral health · 2024Article
- Nattokinase, a Subtilisin-like Alkaline-Serine Protease, Reduces Mutacin Activity by Inactivating the Competence-Stimulating Peptide inPathogens (Basel, Switzerland) · 2024Article
- Oral biofilm composition and phenotype in caries-active and caries-free children.Frontiers in oral health · 2024Article
- mltG gene deletion mitigated virulence potential of Streptococcus mutans: An in-vitro, ex-situ and in-vivo study.AMB Express · 2023Article
- Article
- Oral Microbiome:Frontiers in microbiology · 2022Article
- Genotypic and phenotypic characterization ofIranian journal of microbiology · 2021Article
- Phenotypic and Genotypic Characterization of Streptococcus mutans Strains Isolated from Endodontic Infections.Journal of endodontics · 2020Article
- The enhancing antibiofilm activity of curcumin on Streptococcus mutans strains from severe early childhood caries.BMC microbiology · 2020Article
- Antimicrobial activity and toxicity of glass ionomer cement containing an essential oil.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2020Article
- A Novel Dental Sealant Containing Dimethylaminohexadecyl Methacrylate Suppresses the Cariogenic Pathogenicity ofInternational journal of molecular sciences · 2019Article
- Genotypic diversity of Streptococcus mutans in children with and without early childhood caries- A systematic review.Journal of oral biology and craniofacial researchReview
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Authors and funding
10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly childhood caries (ECC) is an aggressive condition that can affect teeth of young children. This study aimed to evaluate genotypic diversity and phenotypic traits of S. mutans isolated from dental biofilms of children with different caries status in comparison with caries free (CF) children.
methodsStreptococcus mutans strains were isolated from supragingival biofilm samples of CF, ECC and severe-ECC (S-ECC) children and genotyped by arbitrary-primer polymerase chain reaction - AP-PCR. S. mutans genotypes were tested for their ability to reduce the suspension pH through glycolysis, to tolerate extreme acid challenge and by their ability to form biofilm. Response variables were analyzed by ANOVA/Tukey or Kruskal-Wallis/Mann-Whitney tests at a 5% of significance.
resultsThere was an increase in the prevalence of Streptococcus mutans in biofilms with the severity of dental caries. No differences in genotypic diversity and in acidogenicity of genotypes were found among CF, ECC and S-ECC children. S mutans strains with genotypes more characteristic for ECC and S-ECC children formed more biofilms than those identified in CF children. The strains isolated from S-ECC children were highly acid tolerant.
conclusionAlthough S. mutans genotypic diversity was similar among the groups of children, phenotypic traits of S. mutans, especially the acid tolerance response, could explain the severity of early childhood caries.
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