Evidence map›Paper›PMID 28708973›Full record

ArticleVirology2017

Concordance of Beta-papillomavirus across anogenital and oral anatomic sites of men: The HIM Study.

Emily M Nunes, Rossana V M López, Staci L Sudenga, Tarik Gheit, Massimo Tommasino, Maria L Baggio, Silvaneide Ferreira, Lenice Galan, Roberto C Silva, Eduardo Lazcano-Ponce and 4 more

Open access · greenAbstract read
In one paragraph

Article in Virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 4 countries.

Emily M NunesMolecular Biology Laboratory, Center for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Rossana V M LópezDepartment of Epidemiology, Center for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Staci L SudengaDivision of Epidemiology, Vanderbilt University Medical Center, Nashville, TN, USA.
Tarik GheitInfections and Cancer Biology Group, International Agency for Cancer Research (IARC), Lyon, France.
Massimo TommasinoInfections and Cancer Biology Group, International Agency for Cancer Research (IARC), Lyon, France.
Maria L BaggioMolecular Biology Laboratory, Center for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Silvaneide FerreiraMolecular Biology Laboratory, Center for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Lenice GalanLudwig Institute for Cancer Research, São Paulo branch, São Paulo, Brazil.
Roberto C SilvaCentro de Referência e Treinamento DST/AIDS, São Paulo, Brazil.
Eduardo Lazcano-PonceCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, Mexico.
Anna R GiulianoDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Luisa L VillaMolecular Biology Laboratory, Center for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Department of Radiology and Oncology, School of Medicine, University of São Paulo, São Paulo, Brazil.
Laura SicheroMolecular Biology Laboratory, Center for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil. Electronic address: laura.sichero@hc.fm.usp.br.
HIM Study group
Instituto do Câncer do Estado de São Paulo · BRCentre international de recherche sur le cancer · FRInstituto Nacional de Salud Pública · MXInstituto Paulo Gontijo · BRMoffitt Cancer Center · USUniversidade de São Paulo · BRVanderbilt University Medical Center · US

Funding

Natural History of HPV Infection in Men: The HIM StudyR01CA098803 · NCI · H. LEE MOFFITT CANCER CTR &RES INST · PI GIULIANO, ANNA R. · 2004 to 2014
$18.2M
NCI NIH HHS R01 CA098803World Health Organization 001
6 · The paper itself

Abstract

We evaluated the concordance between β-HPVs detected in external genital skin, anal canal, and oral cavity specimens collected simultaneously from 717 men that were participating in the multinational HIM Study. Viral genotyping was performed using the Luminex technology. Species- and type-specific concordance was measured using kappa statistics for agreement. Overall, concordance of β-HPVs across sites was low and mainly observed among paired genital/anal canal samples. When grouped by species, solely β-4 HPVs showed moderate concordance in genital/anal pairs (κ = 0.457), which could be attributed to the substantial concordance of HPV-92 in men from Brazil and Mexico (κ > 0.610). β-HPV type concordance was higher in Mexico, where HPV-19 was consistently concordant in all anatomic site combinations. Our analysis indicates that type-specific concordance across sites is limited to few viral types; however, these infections seem to occur more often than would be expected by chance, suggesting that although rare, there is agreement among sites.

Indexed as

GenotypeAnal CanalBetapapillomavirusBrazilFloridaGenitalia, MaleGenotyping TechniquesHomosexuality, MaleHumansMaleMexicoMouth MucosaPapillomavirus InfectionsAnogenitalConcordanceCutaneous human papillomavirusHIM StudyMalesOral

Identifiers

PMID28708973
PMCPMC6561082
OpenAlexW2736167260

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.