ReviewHuman vaccines & immunotherapeutics2018
Influenza vaccination in the elderly.
Review in Human vaccines & immunotherapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
103 citing papers in PubMed, 2 syntheses or guidelines pooled it, 162 citations in OpenAlex.
- A Systematic Review and Meta-Analysis of Immunogenicity and Safety of the Influenza Vaccine in COPD Patients, and Its Relevance with Real-World Effectiveness.International journal of chronic obstructive pulmonary disease · 2026Pooled it
- Protective effect of influenza vaccination on cardiovascular diseases: a systematic review and meta-analysis.Scientific reports · 2020Pooled it
- Digital Health Intervention on Awareness of Vaccination Against Influenza Among Adults With Diabetes: Pragmatic Randomized Follow-Up Study.Journal of medical Internet research · 2025Trial
- The effect of standard-dose wintertime vitamin D supplementation on influenza infection in immunized nursing home elderly residents.Croatian medical journal · 2021Trial
- Immunogenicity and safety of high-dose quadrivalent influenza vaccine in Japanese adults ≥65 years of age: a randomized controlled clinical trial.Human vaccines & immunotherapeutics · 2020Trial
- Heterogeneity in the psychological antecedents of influenza vaccination among Chinese older adults: A 5C model approach.Human vaccines & immunotherapeutics · 2026Article
- Factors associated with influenza vaccine uptake and intention among public transportation drivers: A cross-sectional study from Lebanon.Human vaccines & immunotherapeutics · 2026Article
- Global Burden of Upper Airway Infections: Epidemiology, Current Challenges and Future Perspectives.Infectious disease reports · 2026Review
- Vaccination in individuals with Down syndrome: immune vulnerability, safety, efficacy and opportunities.NPJ vaccines · 2026Review
- Determinants of influenza vaccination uptake in older adults: findings from a retrospective cross-sectional study.BMC public health · 2026Article
- Vaccination Coverage of Greek Adults Aged ≥60 Years in a Primary Health Care Setting in Relation to Lifestyle Factors and Health Care Services Utilization.Healthcare (Basel, Switzerland) · 2026Article
- Influenza Vaccination Responses in Disabled Stroke Patients: A Single-Center Prospective Observational Study.Annals of clinical and translational neurology · 2026Article
- Article
- Influenza vaccine hesitancy and its influencing factors among community-dwelling older adults in Shihezi City, Xinjiang, Western China.Frontiers in public health · 2026Article
- Aging and Viral Respiratory Infections: Focus on Vitamin D and Microbiota.BioMed research international · 2026Review
- Aging and vaccines: impact of immunosenescence and inflammaging in vaccine response.Frontiers in aging · 2026Review
- Limited Predictive Utility of Baseline Peripheral Blood Bulk Transcriptomics for Influenza Vaccine Responsiveness in Older Adults.Vaccines · 2025Article
- Factors Influencing Influenza Vaccination: A Survey-Based Cross-Sectional Study in the City of Syracuse, Italy.Journal of community health · 2025Article
- Influenza Vaccination in the Elderly in Three Cities in China: Current Status and Influencing Factors Under Different Funding Policies.Vaccines · 2025Article
- Interim Vaccine Effectiveness Against Influenza and Hospitalization, Republic of Korea, 2024-2025 (HIMM Network).Vaccines · 2025Article
43 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seasonal influenza is a prevalent and serious annual illness resulting in widespread morbidity and economic disruption throughout the population; the elderly and immunocompromised are particularly vulnerable to serious sequelae and mortality. The changing demographics worldwide to an aging society have important implications for public health policy and pharmaceutical innovations. For instance, primary prevention via immunization is effective in reducing the burden of influenza illness among the elderly. However, the elderly may be insufficiently protected by vaccination due to the immunosenescence which accompanies aging. In addition, vaccine hesitancy among the younger populations increases the likelihood of circulating infectious diseases, and thus concomitant exposure. While it is clear that the development of more immunogenic vaccines is an imperative and worthy endeavor, clinical trials continue to demonstrate that the current influenza vaccine formulation remains highly effective in reducing morbidity and mortality when well matched to circulating strains.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.