Evidence map›Paper›PMID 28708953›Full record

ArticleHuman vaccines & immunotherapeutics2018

Trends of influenza B during the 2010-2016 seasons in 2 regions of north and south Italy: The impact of the vaccine mismatch on influenza immunisation strategy.

Andrea Orsi, Giuseppina Maria Elena Colomba, Fanny Pojero, Giuseppe Calamusa, Cristiano Alicino, Cecilia Trucchi, Paola Canepa, Filippo Ansaldi, Francesco Vitale, Fabio Tramuto

Open access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
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  3. Review
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  8. Surveillance Data for Eight Consecutive Influenza Seasons in Sicily, Italy.The American journal of tropical medicine and hygiene · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. [The universal influenza vaccination in children with Vaxigrip TetraJournal of preventive medicine and hygiene · 2018
    Article
  14. 100 years since the 1918 influenza pandemic.Human vaccines & immunotherapeutics · 2018
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Andrea Orsia Department of Health Sciences , University of Genoa , Genoa , Italy.ORCID 0000-0002-2433-9610
Giuseppina Maria Elena Colombac Department of Health Promotion Sciences and Mother-Child Care "G. D'Alessandro" - Hygiene section , University of Palermo , Palermo , Italy.ORCID 0000-0003-0465-5445
Fanny Pojeroc Department of Health Promotion Sciences and Mother-Child Care "G. D'Alessandro" - Hygiene section , University of Palermo , Palermo , Italy.ORCID 0000-0002-4971-240X
Giuseppe Calamusac Department of Health Promotion Sciences and Mother-Child Care "G. D'Alessandro" - Hygiene section , University of Palermo , Palermo , Italy.ORCID 0000-0002-6780-5044
Cristiano Alicinoa Department of Health Sciences , University of Genoa , Genoa , Italy.ORCID 0000-0002-6473-9870
Cecilia Trucchia Department of Health Sciences , University of Genoa , Genoa , Italy.ORCID 0000-0003-4633-202X
Paola Canepaa Department of Health Sciences , University of Genoa , Genoa , Italy.ORCID 0000-0002-7294-6618
Filippo Ansaldia Department of Health Sciences , University of Genoa , Genoa , Italy.ORCID 0000-0002-0413-9443
Francesco Vitalec Department of Health Promotion Sciences and Mother-Child Care "G. D'Alessandro" - Hygiene section , University of Palermo , Palermo , Italy.ORCID 0000-0002-6354-8060
Fabio Tramutoc Department of Health Promotion Sciences and Mother-Child Care "G. D'Alessandro" - Hygiene section , University of Palermo , Palermo , Italy.ORCID 0000-0003-0108-4608
University of Genoa · ITUniversity of Palermo · ITAzienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo · ITOspedale Policlinico San Martino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza A and B viruses are responsible for respiratory infections, representing globally seasonal threats to human health. The 2 viral types often co-circulate and influenza B plays an important role in the spread of infection. A 6-year retrospective surveillance study was conducted between 2010 and 2016 in 2 large administrative regions of Italy, located in the north (Liguria) and in the south (Sicily) of the country, to describe the burden and epidemiology of both B/Victoria and B/Yamagata lineages in different healthcare settings. Influenza B viruses were detected in 5 of 6 seasonal outbreaks, exceeding influenza A during the season 2012-2013. Most of influenza B infections were found in children aged ≤ 14 y and significant differences were observed in the age-groups infected by the different lineages. B/Victoria strains prevailed in younger population than B/Yamagata, but also were more frequently found in the community setting. Conversely, B/Yamagata viruses were prevalent among hospitalized cases suggesting their potential role in the development of more severe disease. The relative proportions of viral lineages varied from year to year, resulting in different lineage-level mismatch for the B component of trivalent influenza vaccine. Our findings confirmed the need for continuous virological surveillance of seasonal epidemics and bring attention to the adoption of universal influenza immunization program in the childhood. The use of tetravalent vaccine formulations may be useful to improve the prevention and control of the influenza burden in general population.

Indexed as

ChildChild, PreschoolDisease OutbreaksEpidemicsFemaleHumansInfluenza A virusInfluenza B virusInfluenza, HumanInfluenza VaccinesMaleRetrospective StudiesSeasonsSicilyVaccinationInfluenza VaccinesB/VictoriaB/YamagatacommunityhospitalInfluenza type Blineagevaccine-mismatch

Identifiers

PMID28708953
PMCPMC5861802
OpenAlexW2734986287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.