ArticleACS chemical biology2017
Chemical Genomics, Structure Elucidation, and in Vivo Studies of the Marine-Derived Anticlostridial Ecteinamycin.
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Article in ACS chemical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Chemistry and biology of specialized metabolites produced byNatural product reports · 2024Review
- Tunicates as Sources of High-Quality Nutrients and Bioactive Compounds for Food/Feed and Pharmaceutical Applications: A Review.Foods (Basel, Switzerland) · 2023Review
- Rediscovery of Tetronomycin as a Broad-Spectrum and Potent Antibiotic against Drug-Resistant Gram-Positive Bacteria.ACS omega · 2023Article
- Exploring Oceans for Curative Compounds: Potential New Antimicrobial and Anti-Virulence Molecules againstMarine drugs · 2022Review
- Escaping mechanisms of ESKAPE pathogens from antibiotics and their targeting by natural compounds.Biotechnology reports (Amsterdam, Netherlands) · 2022Article
- Discovery of Marine Natural Products as Promising Antibiotics againstMarine drugs · 2022Review
- Natural Products from Actinomycetes Associated with Marine Organisms.Marine drugs · 2021Review
- Symbiotic Associations in Ascidians: Relevance for Functional Innovation and Bioactive Potential.Marine drugs · 2021Review
- Review
- Expanding the antibacterial selectivity of polyether ionophore antibiotics through diversity-focused semisynthesis.Nature chemistry · 2021Article
- Culture-Dependent Microbiome of theMicroorganisms · 2020Article
- The Ascidian-Derived Metabolites with Antimicrobial Properties.Antibiotics (Basel, Switzerland) · 2020Review
- Antimicrobial compounds from marine actinomycetes.Archives of pharmacal research · 2020Review
- Origins and Bioactivities of Natural Compounds Derived from Marine Ascidians and Their Symbionts.Marine drugs · 2019Review
- Modified Mouse Model of Clostridioides difficile Infection as a Platform for Probiotic Efficacy Studies.Antimicrobial agents and chemotherapy · 2019Article
- Biological and Chemical Diversity of Ascidian-Associated Microorganisms.Marine drugs · 2018Review
- Progressive Stereo Locking (PSL): A Residual Dipolar Coupling Based Force Field Method for Determining the Relative Configuration of Natural Products and Other Small Molecules.ACS chemical biology · 2017Article
Corrections and comments
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Authors and funding
19 authors at 4 institutions in 2 countries.
Thomas P WychePharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison , Madison, Wisconsin 53705, United States.ORCID 0000-0003-4703-741X
René F Ramos AlvarengaPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison , Madison, Wisconsin 53705, United States.
Jeff S PiotrowskiYumanity Therapeutics , Cambridge, Massachusetts 02139, United States.
Megan N DusterDepartment of Medicine, University of Wisconsin-Madison , Madison, Wisconsin 53705, United States.
Simone R WarrackDepartment of Medicine, University of Wisconsin-Madison , Madison, Wisconsin 53705, United States.
Gabriel CornilescuNational Magnetic Resonance Facility at Madison, Department of Biochemistry, University of Wisconsin-Madison , Madison, Wisconsin 53706, United States.ORCID 0000-0002-1204-8904
Travis J De WolfeDepartment of Food Science, University of Wisconsin-Madison , Madison, Wisconsin 53706, United States.ORCID 0000-0001-6261-1235
Yanpeng HouPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison , Madison, Wisconsin 53705, United States.
Doug R BraunPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison , Madison, Wisconsin 53705, United States.
Gregory A EllisPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison , Madison, Wisconsin 53705, United States.
Scott W SimpkinsDepartment of Computer Science and Engineering, University of Minnesota-Twin Cities , Minneapolis, Minnesota 55455, United States.
Justin NelsonDepartment of Computer Science and Engineering, University of Minnesota-Twin Cities , Minneapolis, Minnesota 55455, United States.
Chad L MyersDepartment of Computer Science and Engineering, University of Minnesota-Twin Cities , Minneapolis, Minnesota 55455, United States.
James SteeleDepartment of Food Science, University of Wisconsin-Madison , Madison, Wisconsin 53706, United States.
Hirotada MoriGraduate School of Biological Sciences, Nara Institute of Science and Technology , Ikoma, Nara 630-0101, Japan.
Nasia SafdarDepartment of Medicine, University of Wisconsin-Madison , Madison, Wisconsin 53705, United States.
John L MarkleyNational Magnetic Resonance Facility at Madison, Department of Biochemistry, University of Wisconsin-Madison , Madison, Wisconsin 53706, United States.ORCID 0000-0003-1799-6134
Scott R RajskiPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison , Madison, Wisconsin 53705, United States.
Tim S BugniPharmaceutical Sciences Division, School of Pharmacy, University of Wisconsin-Madison , Madison, Wisconsin 53705, United States.ORCID 0000-0002-4502-3084
University of Wisconsin–Madison · USUniversity of Minnesota · USNara Institute of Science and Technology · JPYumanity Therapeutics (United States) · US
Funding
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2MTR&D 3: TECHNOLOGY DEVELOPMENT FOR NMR STUDIES OF SMALL MOLECULES (METABOLOMICS, NATURAL PRODUCTS, METABOLITE-PROTEIN INTERACTIONS) pp.537-585 P41GM103399 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI MARKLEY, JOHN LUTE · 2012 to 2019
$9.4MMapping the reference genetic network of a eukaryotic cellR01HG005853 · NHGRI · UNIVERSITY OF TORONTO · PI ANDREWS, BRENDA JEAN, BOONE, CHARLES · 2010 to 2025
$7.6MMethods for large-scale analysis of chemical-genetic interactionsR01HG005084 · NHGRI · UNIVERSITY OF MINNESOTA · PI MYERS, CHAD L · 2010 to 2022
$2.9MOmics approaches for natural products discoveryR01GM104192 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BUGNI, TIMOTHY S · 2013 to 2019
$2.0MSparse Structural Equation Models for Gene Networks and Chemical GenomicsR01GM104975 · NIGMS · UNIVERSITY OF MIAMI CORAL GABLES · PI CAI, XIAODONG · 2012 to 2016
$1.8MWIDE-BORE 9.4 TESLA NMR SPECTROMETER FOR UW-MADISONS10RR002781 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI MARKLEY, JOHN L · 1986 to 1986
–CONSOLE UPGRADES FOR NMR FACILITYS10RR008438 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI MARKLEY, JOHN L · 1993 to 1993
–NCATS NIH HHS UL1 TR000427NCRR NIH HHS S10 RR002781NCRR NIH HHS S10 RR008438NHGRI NIH HHS R01 HG005084NHGRI NIH HHS R01 HG005853NIGMS NIH HHS P41 GM103399NIGMS NIH HHS R01 GM104192NIGMS NIH HHS R01 GM104975
Abstract
A polyether antibiotic, ecteinamycin (1), was isolated from a marine Actinomadura sp., cultivated from the ascidian Ecteinascidia turbinata.
Indexed as
ActinomycetalesAnimalsAnti-Bacterial AgentsClostridioides difficileEnterocolitis, PseudomembranousEthersHumansIonophoresUrochordataAnti-Bacterial AgentsEthersIonophores
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