Evidence map›Paper›PMID 28708304›Full record

ArticleNMR in biomedicine2017

Hyperpolarized

Celine Baligand, Hecong Qin, Aisha True-Yasaki, Jeremy W Gordon, Cornelius von Morze, Justin Delos Santos, David M Wilson, Robert Raffai, Patrick M Cowley, Anthony J Baker and 3 more

Open access · greenAbstract read
In one paragraph

Article in NMR in biomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 33 citations in OpenAlex.

  1. Uncoupling proximal tubule ammoniagenesis from bicarbonate generation byAmerican journal of physiology. Renal physiology · 2026
    Article
  2. Review
  3. Assessment of Acute Kidney Injury using MRI.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Biomedical Applications of the Dynamic Nuclear Polarization and Parahydrogen Induced Polarization Techniques for HyperpolarizedMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2021
    Review
  14. Article
  15. Hyperpolarized Carbon (Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  16. Review
  17. HyperpolarisedMagma (New York, N.Y.) · 2020
    Review
  18. HyperpolarizedRadiology · 2019
    Review
  19. Detecting liver injury non-invasively using hyperpolarizedLiver international : official journal of the International Association for the Study of the Liver · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Celine BaligandRadiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
Hecong QinRadiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
Aisha True-YasakiRadiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
Jeremy W GordonRadiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
Cornelius von MorzeRadiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
Justin Delos SantosRadiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
David M WilsonRadiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
Robert RaffaiMedicine, San Francisco VAMC/University of California San Francisco, San Francisco, California, USA.
Patrick M CowleyMedicine, San Francisco VAMC/University of California San Francisco, San Francisco, California, USA.
Anthony J BakerMedicine, San Francisco VAMC/University of California San Francisco, San Francisco, California, USA.
John KurhanewiczRadiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.
David H LovettMedicine, San Francisco VAMC/University of California San Francisco, San Francisco, California, USA.
Zhen Jane WangRadiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA.ORCID http://orcid.org/0000-0002-2065-5296
University of California, San Francisco · USSan Francisco VA Medical Center · US

Funding

TR&D3: Open-Source Tools for Processing Hyperpolarized MR DataP41EB013598 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Daniel B Vigneron · 2011 to 2026
$19.9M
Pathology of Renal Matrix MetabolismR01DK039776 · NIDDK · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI LOVETT, DAVID H · 1987 to 2009
$3.0M
Ascorbate-based biomarkers for predicting radiation response in prostate cancerR01CA166766 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WILSON, DAVID M · 2012 to 2016
$2.4M
Hyperpolarized 13C Markers of Diabetic Nephropathy and Treatment ResponseR01DK097357 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WANG, ZHEN JANE · 2013 to 2017
$1.2M
Mitochondrial Matrix Metalloproteinase-2 and Cardiac InjuryI01BX000593 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI LOVETT, DAVID H · 2009 to 2014
–
Right Heart Function in Health and Chronic Lung DiseaseI01BX000740 · VA · VETERANS AFFAIRS MED CTR SAN FRANCISCO · PI Anthony J. BAKER · 2011 to 2026
–
BLRD VA I01 BX000593BLRD VA I01 BX000740NCI NIH HHS R01 CA166766NIBIB NIH HHS P41 EB013598NIDDK NIH HHS R01 DK039776NIDDK NIH HHS R01 DK097357
6 · The paper itself

Abstract

Acute kidney injury (AKI) is a major risk factor for the development of chronic kidney disease (CKD). Persistent oxidative stress and mitochondrial dysfunction are implicated across diverse forms of AKI and in the transition to CKD. In this study, we applied hyperpolarized (HP)

Indexed as

Carbon-13 Magnetic Resonance SpectroscopyAnimalsBlood Urea NitrogenBody WeightDehydroascorbic AcidDisease Models, AnimalKidneyL-Lactate DehydrogenaseMaleMiceOrgan SizePyruvate Dehydrogenase ComplexPyruvic AcidReperfusion InjuryDehydroascorbic AcidL-Lactate DehydrogenasePyruvate Dehydrogenase ComplexPyruvic Acid[1−13C]dehydroascorbic acid[1−13C]pyruvateAcute kidney injuryhyperpolarizationmagnetic resonance spectroscopymitochondrial dysfunctionoxidative stress

Identifiers

PMID28708304
PMCPMC5618802
OpenAlexW2734471890

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.