Evidence map›Paper›PMID 28708072›Full record

Trial reportNutrients2017

Iron Fortified Complementary Foods Containing a Mixture of Sodium Iron EDTA with Either Ferrous Fumarate or Ferric Pyrophosphate Reduce Iron Deficiency Anemia in 12- to 36-Month-Old Children in a Malaria Endemic Setting: A Secondary Analysis of a Cluster-Randomized Controlled Trial.

Dominik Glinz, Rita Wegmüller, Mamadou Ouattara, Victorine G Diakité, Grant J Aaron, Lorenz Hofer, Michael B Zimmermann, Lukas G Adiossan, Jürg Utzinger, Eliézer K N'Goran and 1 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Dominik GlinzLaboratory of Human Nutrition, Institute of Food, Nutrition, and Health, ETH Zurich, CH-8092 Zurich, Switzerland. dominik.glinz@usb.ch.
Rita WegmüllerLaboratory of Human Nutrition, Institute of Food, Nutrition, and Health, ETH Zurich, CH-8092 Zurich, Switzerland. rita@groundworkhealth.org.
Mamadou OuattaraUnité de Formation et de Recherche Biosciences, Université Félix Houphouët-Boigny, 01 BP V34 Abidjan, Cote d'Ivoire. mamadou_ouatt@yahoo.fr.
Victorine G DiakitéCentre Suisse de Recherches Scientifiques en Côte d'Ivoire, 01 BP 1303 Abidjan, Côte d'Ivoire. sebagnoh@gmail.com.
Grant J AaronGlobal Alliance for Improved Nutrition, CH-1202 Geneva, Switzerland. gjaaron@masimo.com.
Lorenz HoferSwiss Tropical and Public Health Institute, CH-4051 Basel, Switzerland. lhofer92@gmail.com.
Michael B ZimmermannLaboratory of Human Nutrition, Institute of Food, Nutrition, and Health, ETH Zurich, CH-8092 Zurich, Switzerland. michael.zimmermann@hest.ethz.ch.
Lukas G AdiossanHôpital Général de Taabo, Taabo Cité, BP 700 Toumodi, Côte d'Ivoire. adiossanlukas@yahoo.fr.
Jürg UtzingerUniversity of Basel, CH-4003 Basel, Switzerland. juerg.utzinger@swisstph.ch.
Eliézer K N'GoranUnité de Formation et de Recherche Biosciences, Université Félix Houphouët-Boigny, 01 BP V34 Abidjan, Cote d'Ivoire. eliezerngoran@yahoo.fr.
Richard F HurrellLaboratory of Human Nutrition, Institute of Food, Nutrition, and Health, ETH Zurich, CH-8092 Zurich, Switzerland. richard.hurrell@hest.ethz.ch.
ETH Zurich · CHSwiss Centre for Scientific Research · CISwiss Tropical and Public Health Institute · CHGlobal Alliance for Improved Nutrition · CHUniversité Alassane Ouattara · CIUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron deficiency anemia (IDA) is a major public health problem in sub-Saharan Africa. The efficacy of iron fortification against IDA is uncertain in malaria-endemic settings. The objective of this study was to evaluate the efficacy of a complementary food (CF) fortified with sodium iron EDTA (NaFeEDTA) plus either ferrous fumarate (FeFum) or ferric pyrophosphate (FePP) to combat IDA in preschool-age children in a highly malaria endemic region. This is a secondary analysis of a nine-month cluster-randomized controlled trial conducted in south-central Côte d'Ivoire. 378 children aged 12-36 months were randomly assigned to no food intervention (

Indexed as

Infant Nutritional Physiological PhenomenaAnemia, Iron-DeficiencyChild, PreschoolCluster AnalysisCote d'IvoireDiphosphatesEdetic AcidEndemic DiseasesFerric CompoundsFerritinsFerrous CompoundsFood, FortifiedGlycine maxHemoglobinsHumansInfantDiphosphatesEdetic AcidFe(III)-EDTAFerric Compoundsferric pyrophosphateFerritinsFerrous Compoundsferrous fumarateHemoglobinsIronIron, Dietaryanemiacluster-randomized controlled trialcomplementary foodCôte d’Ivoireinfant cerealiron deficiencyiron fortificationPlasmodium falciparumsodium iron EDTA

Identifiers

PMID28708072
PMCPMC5537873
OpenAlexW2735040153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.