Evidence map›Paper›PMID 28708069›Full record

ArticleInternational journal of molecular sciences2017

Distinct Mechanisms Underlying Resveratrol-Mediated Protection from Types of Cellular Stress in C6 Glioma Cells.

John C Means, Bryan C Gerdes, Peter Koulen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

John C MeansVision Research Center, Department of Ophthalmology, School of Medicine, University of Missouri-Kansas City, 2411 Holmes St., Kansas City, MO 64108, USA. meanscj@umkc.edu.
Bryan C GerdesVision Research Center, Department of Ophthalmology, School of Medicine, University of Missouri-Kansas City, 2411 Holmes St., Kansas City, MO 64108, USA. gerdesbc@umkc.edu.
Peter KoulenVision Research Center, Department of Ophthalmology, School of Medicine, University of Missouri-Kansas City, 2411 Holmes St., Kansas City, MO 64108, USA. koulenp@umkc.edu.
University of Missouri–Kansas City · US

Funding

Protein Targets of Oxidative Brain AgingP01AG022550 · NIA · WEST VIRGINIA UNIVERSITY · PI SIMPKINS, JAMES W. · 2003 to 2013
$15.7M
ROLE OF MITHOCHONDRIAL ERB IN NEURONAL VULNDERABILITY TO NEUROTOXIC STRESSP01AG027956 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI SINGH, MEHARVAN · 2007 to 2017
$11.3M
Novel mechanism of action as therapeutic strategy for optic neuritisR01EY022774 · NEI · UNIVERSITY OF MISSOURI KANSAS CITY · PI KOULEN, PETER · 2012 to 2014
$1.2M
Confocal Laser Scanning MicroscopeS10RR027093 · NCRR · UNIVERSITY OF MISSOURI KANSAS CITY · PI KOULEN, PETER · 2010 to 2010
$497k
NCRR NIH HHS S10 RR027093NEI NIH HHS R01 EY022774NIA NIH HHS P01 AG022550NIA NIH HHS P01 AG027956
6 · The paper itself

Abstract

The polyphenolic phytostilbene,

Indexed as

AnimalsApoptosisCaspasesCell Line, TumorCytoprotectionDNA DamageEnzyme ActivationGliomaModels, BiologicalNeurofibrillary TanglesOxidative StressPhosphorylationPhosphoserineRatsResveratrolSignal TransductionCaspasesPhosphoserineResveratrolStilbenestau Proteinscaspasecentral nervous systemDNA damageglianeurofibrillary tanglesoxidative stresstauopathy

Identifiers

PMID28708069
PMCPMC5536011
OpenAlexW2734585614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.