Evidence map›Paper›PMID 28708001›Full record

ArticleApplied spectroscopy2017

Applying Full Spectrum Analysis to a Raman Spectroscopic Assessment of Fracture Toughness of Human Cortical Bone.

Alexander J Makowski, Mathilde Granke, Oscar D Ayala, Sasidhar Uppuganti, Anita Mahadevan-Jansen, Jeffry S Nyman

Open access · bronzeAbstract read
In one paragraph

Article in Applied spectroscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  15. Spatially offset Raman spectroscopy forBiomedical optics express · 2018
    Article
  16. Bone health in type 1 diabetes.Current opinion in endocrinology, diabetes, and obesity · 2018
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alexander J Makowski1 Department of Orthopaedic Surgery and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, USA.
Mathilde Granke1 Department of Orthopaedic Surgery and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, USA.
Oscar D Ayala2 Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
Sasidhar Uppuganti1 Department of Orthopaedic Surgery and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, USA.
Anita Mahadevan-Jansen2 Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
Jeffry S Nyman1 Department of Orthopaedic Surgery and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, USA.
VA Tennessee Valley Healthcare System · USVanderbilt University · USVanderbilt University Medical Center · US

Funding

The Roles of Collagen and Water in the Fracture Resistance of BoneR01AR063157 · NIAMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI NYMAN, JEFFRY STEPHEN · 2012 to 2025
$3.9M
Novel ultrahigh resolution microCT imaging systemS10RR027631 · NCRR · VANDERBILT UNIVERSITY · PI PERRIEN, DANIEL S · 2010 to 2010
$460k
Aging and Diabetes-Related Factors Compromising Bone Fracture ResistanceI01BX001018 · VA · VETERANS HEALTH ADMINISTRATION · PI NYMAN, JEFFRY STEPHEN · 2011 to 2014
–
BLRD VA I01 BX001018NCRR NIH HHS S10 RR027631NIAMS NIH HHS R01 AR063157
6 · The paper itself

Abstract

A decline in the inherent quality of bone tissue is a † Equal contributors contributor to the age-related increase in fracture risk. Although this is well-known, the important biochemical factors of bone quality have yet to be identified using Raman spectroscopy (RS), a nondestructive, inelastic light-scattering technique. To identify potential RS predictors of fracture risk, we applied principal component analysis (PCA) to 558 Raman spectra (370-1720 cm

Indexed as

AdultAgedAged, 80 and overBone DensityCollagenCortical BoneFemaleFractures, BoneHumansMaleMiddle AgedSpectrum Analysis, RamanYoung AdultCollagenbone mineral densityBone qualityfracture riskmultivariateRaman spectroscopytoughness

Identifiers

PMID28708001
PMCPMC5561524
OpenAlexW2625546516

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.